Product Information

PRIMIDONE 250 MG TABLET is a generic product labeled by Advagen Pharma Ltd., priced at $0.2197 per EA under NDC 72888004601. Its NADAC has been published 194 times since Dec 7, 2022.

FDA first approved this application on Jun 28, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PRIMIDONE 250 MG TABLET

Primidone
$0.2197per EA

Strength

250 mg/1

NDC

72888004601

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PRIMIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA214896

FDA Approved

6/28/2022

TE Code

AB

On Market Since

6/28/2022

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for PRIMIDONE 250 MG TABLET has been published 194 times since Dec 7, 2022, and over the history we have for it it has declined 29.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2197 per EA
All-time high$0.3126 (Dec 14, 2022)
All-time low$0.1915 (Nov 20, 2024)
52-week high$0.2741
52-week low$0.2197
Median price$0.2671
Average price$0.2624
Largest weekly change+31.2% (Aug 21, 2024)
Weeks tracked194
Tracking sinceDec 7, 2022

Price History

1W

-1.1%

1M

-1.1%

3M

-6.2%

6M

-5.6%

1Y

-19.8%

3Y

-22.6%

5Y

N/A

All

-29.7%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PRIMIDONE 250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for PRIMIDONE 250 MG TABLET, manufactured by Advagen Pharma Ltd., is $0.2197 per EA (NDC 72888004601), effective Aug 19, 2026.

How has the price of PRIMIDONE 250 MG TABLET changed over time?

Over the history we have for it, the NADAC for PRIMIDONE 250 MG TABLET has declined 29.7%. It has been tracked across 194 weekly CMS publications since Dec 7, 2022.

What are the highest and lowest recorded NADAC prices for PRIMIDONE 250 MG TABLET?

Since Dec 7, 2022, the NADAC for PRIMIDONE 250 MG TABLET has ranged from a low of $0.1915 (Nov 20, 2024) to a high of $0.3126 (Dec 14, 2022), with a median of $0.2671 per EA.

Are there cheaper alternatives to PRIMIDONE 250 MG TABLET?

Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PRIMIDONE 250 MG TABLET, is $0.2102 per EA — about 4% below PRIMIDONE 250 MG TABLET.

Who manufactures PRIMIDONE 250 MG TABLET?

PRIMIDONE 250 MG TABLET (NDC 72888004601) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.