Product Information
AMITRIPTYLINE HCL 10 MG TAB is a generic product labeled by Advagen Pharma Ltd., priced at $0.0299 per EA under NDC 72888006700. Its NADAC has been published 72 times since Apr 9, 2025.
FDA first approved this application on May 1, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888006700
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
AMITRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215376FDA Approved
5/1/2023
TE Code
AB
On Market Since
5/1/2023
Pharmacological Classes
Price Statistics
The NADAC for AMITRIPTYLINE HCL 10 MG TAB has been published 72 times since Apr 9, 2025, and over the history we have for it it has declined 27.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0299 per EA |
|---|---|
| All-time high | $0.0413 (Jun 11, 2025) |
| All-time low | $0.0294 (Jun 17, 2026) |
| 52-week high | $0.0375 |
| 52-week low | $0.0294 |
| Median price | $0.0368 |
| Average price | $0.0360 |
| Largest weekly change | -8.0% (Jun 17, 2026) |
| Weeks tracked | 72 |
| Tracking since | Apr 9, 2025 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of AMITRIPTYLINE HCL 10 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 10 MG TAB, manufactured by Advagen Pharma Ltd., is $0.0299 per EA (NDC 72888006700), effective Aug 19, 2026.
How has the price of AMITRIPTYLINE HCL 10 MG TAB changed over time?
Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 10 MG TAB has declined 27.1%. It has been tracked across 72 weekly CMS publications since Apr 9, 2025.
What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 10 MG TAB?
Since Apr 9, 2025, the NADAC for AMITRIPTYLINE HCL 10 MG TAB has ranged from a low of $0.0294 (Jun 17, 2026) to a high of $0.0413 (Jun 11, 2025), with a median of $0.0368 per EA.
Are there cheaper alternatives to AMITRIPTYLINE HCL 10 MG TAB?
10 manufacturers publish a NADAC-priced product with the same active ingredient and strength as AMITRIPTYLINE HCL 10 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures AMITRIPTYLINE HCL 10 MG TAB?
AMITRIPTYLINE HCL 10 MG TAB (NDC 72888006700) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.