Drug Markets/Amitriptyline Hydrochloride

Amitriptyline Hydrochloride

93 NDCs across 13 manufacturers|93 Generic,0 Brand

Amitriptyline Hydrochloride is used to treat depressive disorder and pain, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 66 AB-rated (therapeutically equivalent) products for this ingredient.

Amitriptyline Hydrochloride is available as 93 NDCs from 13 manufacturers (93 generic, 0 brand), with NADAC prices from $0.03 to $0.31 per EA — the most expensive product costs about 10× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

93G / 0B

Manufacturers

competing in market

Price Spread

$0.03 – $0.31

per EA

7d Activity

59↑31↓3 flat

avg +0.8% WoW · of 93 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

13 manufacturers producing AMITRIPTYLINE HYDROCHLORIDE(4 pricing outliers)

Sun Pharmaceutical Industries Inc.

Westminster Pharmaceuticals LLC

9 NDCs

$0.1010

avg/unit

Rising Pharma Holdings Inc.

9 NDCs

$0.1010

avg/unit

Zydus Pharmaceuticals (USA) Inc.

9 NDCs

$0.1010

avg/unit

Unichem Pharmaceuticals (USA) Inc.

Accord Healthcare Inc.

Major Pharmaceuticals

American Health Packaging

Drug Portfolio

93 NDCs total, 93 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
AMITRIPTYLINE HCL 150 MG TAB	70756020611	Lifestar Pharma LLC	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	00781149101	Sandoz Inc.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	57664069188	Sun Pharmaceutical Industries Inc.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	16714026201	NorthStar Rx LLC	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	69367039301	Westminster Pharmaceuticals LLC	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	16571011001	Rising Pharma Holdings Inc.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	70710123001	Zydus Pharmaceuticals (USA) Inc.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	29300042401	Unichem Pharmaceuticals (USA) Inc.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	72888007201	Advagen Pharma Ltd.	$0.3070 per EA	—	Generic	+1.22%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 150 MG TAB	16729017601	Accord Healthcare Inc.	$0.2921 per EA	High Outlier	Generic	—	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	57664069088	Sun Pharmaceutical Industries Inc.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	50268004115	AvPAK	$0.1455 per EA	Low Outlier	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	69367039201	Westminster Pharmaceuticals LLC	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	29300042301	Unichem Pharmaceuticals (USA) Inc.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	16571010901	Rising Pharma Holdings Inc.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	72888007101	Advagen Pharma Ltd.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	70756020511	Lifestar Pharma LLC	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	00781149001	Sandoz Inc.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	16714026101	NorthStar Rx LLC	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 100 MG TAB	70710122901	Zydus Pharmaceuticals (USA) Inc.	$0.1455 per EA	—	Generic	-0.19%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	57664069288	Sun Pharmaceutical Industries Inc.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	50268004015	AvPAK	$0.1140 per EA	Low Outlier	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	72888007001	Advagen Pharma Ltd.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	70756020411	Lifestar Pharma LLC	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	69367039101	Westminster Pharmaceuticals LLC	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	70710122801	Zydus Pharmaceuticals (USA) Inc.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	16714026001	NorthStar Rx LLC	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	16571010801	Rising Pharma Holdings Inc.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	00781148901	Sandoz Inc.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 75 MG TAB	29300042201	Unichem Pharmaceuticals (USA) Inc.	$0.1140 per EA	—	Generic	+3.55%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	70756020312	Lifestar Pharma LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	00781148801	Sandoz Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	00781148810	Sandoz Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	00904741161	Major Pharmaceuticals	$0.0904 per EA	Low Outlier	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	16571010701	Rising Pharma Holdings Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	16571010710	Rising Pharma Holdings Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	16714025901	NorthStar Rx LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	16714025902	NorthStar Rx LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	72888006901	Advagen Pharma Ltd.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	72888006900	Advagen Pharma Ltd.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	29300042101	Unichem Pharmaceuticals (USA) Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	29300042110	Unichem Pharmaceuticals (USA) Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	50268003915	AvPAK	$0.0904 per EA	Low Outlier	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	57664068918	Sun Pharmaceutical Industries Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	57664068988	Sun Pharmaceutical Industries Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	60687044401	American Health Packaging	$0.0904 per EA	Low Outlier	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	69367039001	Westminster Pharmaceuticals LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	69367039010	Westminster Pharmaceuticals LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	70756020311	Lifestar Pharma LLC	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	70710122700	Zydus Pharmaceuticals (USA) Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 50 MG TAB	70710122701	Zydus Pharmaceuticals (USA) Inc.	$0.0904 per EA	—	Generic	-0.26%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	29300042001	Unichem Pharmaceuticals (USA) Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	60687043301	American Health Packaging	$0.0512 per EA	Low Outlier	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	00781148701	Sandoz Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	16714025802	NorthStar Rx LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	16714025801	NorthStar Rx LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	69367038901	Westminster Pharmaceuticals LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	69367038910	Westminster Pharmaceuticals LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	70756020212	Lifestar Pharma LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	00904741061	Major Pharmaceuticals	$0.0512 per EA	Low Outlier	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	16571010610	Rising Pharma Holdings Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	16571010601	Rising Pharma Holdings Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	29300042010	Unichem Pharmaceuticals (USA) Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	70756020211	Lifestar Pharma LLC	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	00781148710	Sandoz Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	72888006800	Advagen Pharma Ltd.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	50268003815	AvPAK	$0.0512 per EA	Low Outlier	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	57664068818	Sun Pharmaceutical Industries Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	57664068888	Sun Pharmaceutical Industries Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	70710122600	Zydus Pharmaceuticals (USA) Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	70710122601	Zydus Pharmaceuticals (USA) Inc.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 25 MG TAB	72888006801	Advagen Pharma Ltd.	$0.0512 per EA	—	Generic	+0.43%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16729017117	Accord Healthcare Inc.	$0.0375 per EA	High Outlier	Generic	—	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16729017101	Accord Healthcare Inc.	$0.0320 per EA	High Outlier	Generic	—	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	70756020112	Lifestar Pharma LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	70756020111	Lifestar Pharma LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	70710122501	Zydus Pharmaceuticals (USA) Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	70710122500	Zydus Pharmaceuticals (USA) Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	69367038810	Westminster Pharmaceuticals LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	69367038801	Westminster Pharmaceuticals LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	57664068788	Sun Pharmaceutical Industries Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	72888006700	Advagen Pharma Ltd.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	72888006701	Advagen Pharma Ltd.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	57664068718	Sun Pharmaceutical Industries Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	50268003715	AvPAK	$0.0299 per EA	Low Outlier	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	29300041910	Unichem Pharmaceuticals (USA) Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	29300041901	Unichem Pharmaceuticals (USA) Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16714025702	NorthStar Rx LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16714025701	NorthStar Rx LLC	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16571010510	Rising Pharma Holdings Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	16571010501	Rising Pharma Holdings Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	00781148610	Sandoz Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant
AMITRIPTYLINE HCL 10 MG TAB	00781148601	Sandoz Inc.	$0.0299 per EA	—	Generic	+1.42%	Tricyclic Antidepressant

Frequently Asked Questions

What is Amitriptyline Hydrochloride used to treat?

Amitriptyline Hydrochloride is used to treat depressive disorder and pain, per the National Library of Medicine's MED-RT classification.

When did Amitriptyline Hydrochloride become available as a generic?

FDA approved the first generic Amitriptyline Hydrochloride (ANDA) on Jan 1, 1982. The Orange Book currently lists 66 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How many Amitriptyline Hydrochloride products are on the market?

The Amitriptyline Hydrochloride drug market contains 93 NDCs from 13 manufacturers — 93 generic and 0 brand products.

What is the price range for Amitriptyline Hydrochloride?

NADAC reference prices for Amitriptyline Hydrochloride range from $0.0299 to $0.3070 per EA — the most expensive product costs about 10× the cheapest.

Which manufacturers make Amitriptyline Hydrochloride?

13 manufacturers list Amitriptyline Hydrochloride in NADAC. Ranked by number of NDCs, the largest are Lifestar Pharma LLC (9), Sandoz Inc. (9), Sun Pharmaceutical Industries Inc. (9), NorthStar Rx LLC (9), Westminster Pharmaceuticals LLC (9).

How has the price of Amitriptyline Hydrochloride changed recently?

Over the past 7 days, 59 Amitriptyline Hydrochloride NDCs rose and 31 fell, with a market-wide average change of +0.8%.