Product Information
ISOSORBIDE DINITRATE 20 MG TAB is a generic product labeled by Advagen Pharma Ltd., priced at $0.1989 per EA under NDC 72888008301. Its NADAC has been published 200 times since Dec 7, 2022.
FDA first approved this application on Jul 8, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
20 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888008301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ISOSORBIDE DINITRATEApproval Type
Generic (ANDA)
FDA Application
ANDA215723FDA Approved
7/8/2022
TE Code
AB
On Market Since
7/8/2022
Pharmacological Classes
Price Statistics
The NADAC for ISOSORBIDE DINITRATE 20 MG TAB has been published 200 times since Dec 7, 2022, and over the history we have for it it has declined 32.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1989 per EA |
|---|---|
| All-time high | $0.3478 (Feb 15, 2023) |
| All-time low | $0.1888 (Jun 17, 2026) |
| 52-week high | $0.2212 |
| 52-week low | $0.1888 |
| Median price | $0.2421 |
| Average price | $0.2521 |
| Largest weekly change | -29.0% (Apr 17, 2024) |
| Weeks tracked | 200 |
| Tracking since | Dec 7, 2022 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Advagen Pharma Ltd. manufacturer profile
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Drug market
isosorbide dinitrate market comparison
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Therapeutic class
Nitrate Vasodilator class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ISOSORBIDE DINITRATE 20 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for ISOSORBIDE DINITRATE 20 MG TAB, manufactured by Advagen Pharma Ltd., is $0.1989 per EA (NDC 72888008301), effective Sep 30, 2026.
How has the price of ISOSORBIDE DINITRATE 20 MG TAB changed over time?
Over the history we have for it, the NADAC for ISOSORBIDE DINITRATE 20 MG TAB has declined 32.8%. It has been tracked across 200 weekly CMS publications since Dec 7, 2022.
What are the highest and lowest recorded NADAC prices for ISOSORBIDE DINITRATE 20 MG TAB?
Since Dec 7, 2022, the NADAC for ISOSORBIDE DINITRATE 20 MG TAB has ranged from a low of $0.1888 (Jun 17, 2026) to a high of $0.3478 (Feb 15, 2023), with a median of $0.2421 per EA.
Are there cheaper alternatives to ISOSORBIDE DINITRATE 20 MG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOSORBIDE DINITRATE 20 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOSORBIDE DINITRATE 20 MG TAB?
ISOSORBIDE DINITRATE 20 MG TAB (NDC 72888008301) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.