Product Information

CIPROFLOXACIN 0.3% EYE DROP is a generic product labeled by Advagen Pharma Ltd., priced at $3.2017 per ML under NDC 72888010221. Its NADAC has been published 54 times since Aug 13, 2025.

FDA first approved this application on Jun 9, 2004. Its Orange Book therapeutic-equivalence code is AT.

CIPROFLOXACIN 0.3% EYE DROP

CIPROFLOXACIN HYDROCHLORIDE
$3.2017per ML

Strength

3 mg/mL

NDC

72888010221

Classification

Generic

Dosage Form

SOLUTION

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

CIPROFLOXACIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075928

FDA Approved

6/9/2004

TE Code

AT

On Market Since

3/16/2022

Pharmacological Classes

Cytochrome P450 1A2 Inhibitors
Fluoroquinolone Antibacterial
Fluoroquinolones

Price Statistics

The NADAC for CIPROFLOXACIN 0.3% EYE DROP has been published 54 times since Aug 13, 2025, and over the history we have for it it has risen 19.6%. The table below summarizes its recorded NADAC range and movement.

Current price$3.2017 per ML
All-time high$3.2017 (Aug 19, 2026)
All-time low$2.6764 (Aug 13, 2025)
52-week high$3.2017
52-week low$2.7946
Median price$2.8936
Average price$2.8823
Largest weekly change+8.6% (Aug 19, 2026)
Weeks tracked54
Tracking sinceAug 13, 2025

Price History

1W

+8.6%

1M

+8.6%

3M

+10.3%

6M

+14.6%

1Y

+14.4%

3Y

N/A

5Y

N/A

All

+19.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 75% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 75%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of CIPROFLOXACIN 0.3% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for CIPROFLOXACIN 0.3% EYE DROP, manufactured by Advagen Pharma Ltd., is $3.2017 per ML (NDC 72888010221), effective Aug 19, 2026.

How has the price of CIPROFLOXACIN 0.3% EYE DROP changed over time?

Over the history we have for it, the NADAC for CIPROFLOXACIN 0.3% EYE DROP has risen 19.6%. It has been tracked across 54 weekly CMS publications since Aug 13, 2025.

What are the highest and lowest recorded NADAC prices for CIPROFLOXACIN 0.3% EYE DROP?

Since Aug 13, 2025, the NADAC for CIPROFLOXACIN 0.3% EYE DROP has ranged from a low of $2.6764 (Aug 13, 2025) to a high of $3.2017 (Aug 19, 2026), with a median of $2.8936 per ML.

Are there cheaper alternatives to CIPROFLOXACIN 0.3% EYE DROP?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CIPROFLOXACIN 0.3% EYE DROP, is $0.7990 per ML — about 75% below CIPROFLOXACIN 0.3% EYE DROP.

Who manufactures CIPROFLOXACIN 0.3% EYE DROP?

CIPROFLOXACIN 0.3% EYE DROP (NDC 72888010221) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.