Product Information
PROMETRIUM 100 MG CAPSULE is a brand product labeled by Acertis Pharmaceuticals, LLC, priced at $15.9095 per EA under NDC 72989037230. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on May 14, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Progesterone market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
100 mg/1
Manufacturer
Acertis Pharmaceuticals, LLCNDC
72989037230
Classification
Brand
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PROGESTERONEApproval Type
New Drug (NDA)
FDA Application
NDA019781FDA Approved
5/14/1998
TE Code
AB
On Market Since
11/1/2022
Pharmacological Classes
Price Statistics
The NADAC for PROMETRIUM 100 MG CAPSULE has been published 129 times since Apr 17, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $15.9095 per EA |
|---|---|
| All-time high | $16.0575 (Jan 14, 2026) |
| All-time low | $15.9095 (Sep 23, 2026) |
| 52-week high | $16.0575 |
| 52-week low | $15.9095 |
| Median price | $16.0112 |
| Average price | $16.0004 |
| Largest weekly change | +0.3% (Dec 17, 2025) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Acertis Pharmaceuticals, LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Progesterone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Progesterone class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROMETRIUM 100 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for PROMETRIUM 100 MG CAPSULE, manufactured by Acertis Pharmaceuticals, LLC, is $15.9095 per EA (NDC 72989037230), effective Sep 30, 2026.
How has the price of PROMETRIUM 100 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for PROMETRIUM 100 MG CAPSULE has held within roughly two percent of its current level. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for PROMETRIUM 100 MG CAPSULE?
Since Apr 17, 2024, the NADAC for PROMETRIUM 100 MG CAPSULE has ranged from a low of $15.9095 (Sep 23, 2026) to a high of $16.0575 (Jan 14, 2026), with a median of $16.0112 per EA.
Are there cheaper alternatives to PROMETRIUM 100 MG CAPSULE?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PROGESTERONE 100 MG CAPSULE, is $0.2290 per EA — about 99% below PROMETRIUM 100 MG CAPSULE.
Who manufactures PROMETRIUM 100 MG CAPSULE?
PROMETRIUM 100 MG CAPSULE (NDC 72989037230) is labeled by Acertis Pharmaceuticals, LLC, and CMS classifies it as a brand product.