Progesterone
24 NDCs across 13 manufacturers|19 Generic,5 Brand
Progesterone is used to treat amenorrhea, endometrial hyperplasia, female infertility and uterine hemorrhage, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Apr 25, 2001. FDA's Orange Book lists 17 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $8K on Progesterone across 216 claims for 100 beneficiaries.
Progesterone is available as 24 NDCs from 13 manufacturers (19 generic, 5 brand), with NADAC prices from $0.23 to $30.39 per EA — the most expensive product costs about 133× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
24
19G / 5B
Manufacturers
13
competing in market
Price Spread
$0.23 – $30.39
per EA, 17 of 24 NDCs
7d Activity
avg -2.6% WoW · of 24 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Bionpharma Inc. manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Progesterone class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
13 manufacturers producing PROGESTERONE(3 pricing outliers)
Frequently Asked Questions
What is Progesterone used to treat?
Progesterone is used to treat amenorrhea, endometrial hyperplasia, female infertility and uterine hemorrhage, per the National Library of Medicine's MED-RT classification.
When did Progesterone become available as a generic?
FDA approved the first generic Progesterone (ANDA) on Apr 25, 2001. The Orange Book currently lists 17 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Progesterone?
In 2024, Medicare Part D spent $8K on Progesterone across 216 claims for 100 beneficiaries.
How many Progesterone products are on the market?
The Progesterone drug market contains 24 NDCs from 13 manufacturers — 19 generic and 5 brand products.
What is the price range for Progesterone?
NADAC reference prices for Progesterone range from $0.2290 to $30.3947 per EA — the most expensive product costs about 133× the cheapest. 7 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Progesterone cheaper than brand?
The average generic NADAC for Progesterone is $0.3256 per EA, versus $20.4854 for brand-labeled products — brand versions average about 63× the generic price.
Which manufacturers make Progesterone?
13 manufacturers list Progesterone in NADAC. Ranked by number of NDCs, the largest are Bionpharma Inc. (4), Xiromed LLC (3), Acertis Pharmaceuticals, LLC (2), Allergan, Inc. (2), Dr. Reddy's Laboratories Inc. (2).
How has the price of Progesterone changed recently?
Over the past 7 days, 0 Progesterone NDCs rose and 18 fell, with a market-wide average change of -2.6%.