Product Information
LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB is a generic product labeled by Exelan Pharmaceuticals Inc., priced at $0.0408 per EA under NDC 76282044890. Its NADAC has been published 345 times since Feb 26, 2020.
FDA first approved this application on May 23, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 20 mg/1; mg/1
Manufacturer
Exelan Pharmaceuticals Inc.NDC
76282044890
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; LISINOPRILApproval Type
Generic (ANDA)
FDA Application
ANDA204058FDA Approved
5/23/2017
TE Code
AB
On Market Since
5/1/2019
Pharmacological Classes
Price Statistics
The NADAC for LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB has been published 345 times since Feb 26, 2020, and over the history we have for it it has declined 22.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0408 per EA |
|---|---|
| All-time high | $0.0566 (Aug 11, 2021) |
| All-time low | $0.0334 (Nov 20, 2024) |
| 52-week high | $0.0432 |
| 52-week low | $0.0399 |
| Median price | $0.0470 |
| Average price | $0.0464 |
| Largest weekly change | +27.5% (Aug 21, 2024) |
| Weeks tracked | 345 |
| Tracking since | Feb 26, 2020 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Exelan Pharmaceuticals Inc. manufacturer profile
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Drug market
Lisinopril and Hydrochlorothiazide Tablets market comparison
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Therapeutic class
Angiotensin Converting Enzyme Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB, manufactured by Exelan Pharmaceuticals Inc., is $0.0408 per EA (NDC 76282044890), effective Sep 30, 2026.
How has the price of LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB changed over time?
Over the history we have for it, the NADAC for LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB has declined 22.3%. It has been tracked across 345 weekly CMS publications since Feb 26, 2020.
What are the highest and lowest recorded NADAC prices for LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB?
Since Feb 26, 2020, the NADAC for LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB has ranged from a low of $0.0334 (Nov 20, 2024) to a high of $0.0566 (Aug 11, 2021), with a median of $0.0470 per EA.
Are there cheaper alternatives to LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB?
LISINOPRIL-HYDROCHLOROTHIAZIDE 20-25 MG TAB (NDC 76282044890) is labeled by Exelan Pharmaceuticals Inc., and CMS classifies it as a generic product.