Product Information

HYZAAR 100-12.5 TABLET is a brand product labeled by Organon LLC, priced at $6.8200 per EA under NDC 78206014001. Its NADAC has been published 118 times since May 22, 2024.

FDA first approved this application on Apr 28, 1995. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the losartan potassium and hydrochlorothiazide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

HYZAAR 100-12.5 TABLET

losartan potassium and hydrochlorothiazide
$6.8200per EA
High Outlier

Strength

12.5; 100 mg/1; mg/1

Manufacturer

Organon LLC

NDC

78206014001

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

1/1/2026

Approval Type

New Drug (NDA)

FDA Application

NDA020387

FDA Approved

4/28/1995

TE Code

AB

On Market Since

6/1/2021

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for HYZAAR 100-12.5 TABLET has been published 118 times since May 22, 2024, and over the history we have for it it has risen 10.4%. The table below summarizes its recorded NADAC range and movement.

Current price$6.8200 per EA
All-time high$6.8200 (Aug 19, 2026)
All-time low$6.1589 (Sep 18, 2024)
52-week high$6.8200
52-week low$6.4928
Median price$6.4736
Average price$6.4924
Largest weekly change+5.0% (Jan 1, 2025)
Weeks tracked118
Tracking sinceMay 22, 2024

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+5.0%

3Y

N/A

5Y

N/A

All

+10.4%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYZAAR 100-12.5 TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYZAAR 100-12.5 TABLET, manufactured by Organon LLC, is $6.8200 per EA (NDC 78206014001), effective Aug 19, 2026.

How has the price of HYZAAR 100-12.5 TABLET changed over time?

Over the history we have for it, the NADAC for HYZAAR 100-12.5 TABLET has risen 10.4%. It has been tracked across 118 weekly CMS publications since May 22, 2024.

What are the highest and lowest recorded NADAC prices for HYZAAR 100-12.5 TABLET?

Since May 22, 2024, the NADAC for HYZAAR 100-12.5 TABLET has ranged from a low of $6.1589 (Sep 18, 2024) to a high of $6.8200 (Aug 19, 2026), with a median of $6.4736 per EA.

Are there cheaper alternatives to HYZAAR 100-12.5 TABLET?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB, is $0.0750 per EA — about 99% below HYZAAR 100-12.5 TABLET.

Who manufactures HYZAAR 100-12.5 TABLET?

HYZAAR 100-12.5 TABLET (NDC 78206014001) is labeled by Organon LLC, and CMS classifies it as a brand product.