Product Information

ZORYVE 0.15% CREAM is a brand product labeled by Arcutis Biotherapeutics, Inc., priced at $15.3969 per GM under NDC 80610011560. Its NADAC has been published 92 times since Nov 20, 2024.

FDA first approved this application on Jul 29, 2022.

The High Outlier badge above means this manufacturer's average price in the roflumilast market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZORYVE 0.15% CREAM

roflumilast
$15.3969per GM
High Outlier

Strength

1.5 mg/g

NDC

80610011560

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ROFLUMILAST

Approval Type

New Drug (NDA)

FDA Application

NDA215985

FDA Approved

7/29/2022

On Market Since

7/9/2024

Pharmacological Classes

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitors

Price Statistics

The NADAC for ZORYVE 0.15% CREAM has been published 92 times since Nov 20, 2024, and over the history we have for it it has risen 9.2%. The table below summarizes its recorded NADAC range and movement.

Current price$15.3969 per GM
All-time high$15.3996 (Jul 15, 2026)
All-time low$14.0940 (Nov 20, 2024)
52-week high$15.3996
52-week low$14.7762
Median price$14.7870
Average price$14.9500
Largest weekly change+4.0% (Jan 1, 2025)
Weeks tracked92
Tracking sinceNov 20, 2024

Price History

1W

+0.0%

1M

+0.0%

3M

+0.1%

6M

+0.0%

1Y

+4.2%

3Y

N/A

5Y

N/A

All

+9.2%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the roflumilast market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of ZORYVE 0.15% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for ZORYVE 0.15% CREAM, manufactured by Arcutis Biotherapeutics, Inc., is $15.3969 per GM (NDC 80610011560), effective Aug 19, 2026.

How has the price of ZORYVE 0.15% CREAM changed over time?

Over the history we have for it, the NADAC for ZORYVE 0.15% CREAM has risen 9.2%. It has been tracked across 92 weekly CMS publications since Nov 20, 2024.

What are the highest and lowest recorded NADAC prices for ZORYVE 0.15% CREAM?

Since Nov 20, 2024, the NADAC for ZORYVE 0.15% CREAM has ranged from a low of $14.0940 (Nov 20, 2024) to a high of $15.3996 (Jul 15, 2026), with a median of $14.7870 per GM.

Are there cheaper alternatives to ZORYVE 0.15% CREAM?

No other NADAC-published product currently shares the active ingredient and strength of ZORYVE 0.15% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ZORYVE 0.15% CREAM?

ZORYVE 0.15% CREAM (NDC 80610011560) is labeled by Arcutis Biotherapeutics, Inc., and CMS classifies it as a brand product.