Product Information

ZORYVE 0.3% CREAM is a brand product labeled by Arcutis Biotherapeutics, Inc., priced at $15.3781 per GM under NDC 80610013060. Its NADAC has been published 167 times since Apr 19, 2023.

The High Outlier badge above means this manufacturer's average price in the roflumilast market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZORYVE 0.3% CREAM

roflumilast
$15.3781per GM
High Outlier

Strength

3 mg/g

NDC

80610013060

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ROFLUMILAST

Approval Type

New Drug (NDA)

FDA Application

NDA215985

On Market Since

7/29/2022

Pharmacological Classes

Phosphodiesterase 4 Inhibitor
Phosphodiesterase 4 Inhibitors

Price Statistics

The NADAC for ZORYVE 0.3% CREAM has been published 167 times since Apr 19, 2023, and over the history we have for it it has risen 16.1%. The table below summarizes its recorded NADAC range and movement.

Current price$15.3781 per GM
All-time high$15.3897 (May 13, 2026)
All-time low$13.2416 (Apr 19, 2023)
52-week high$15.3897
52-week low$14.7978
Median price$14.2745
Average price$14.3086
Largest weekly change+4.0% (Nov 22, 2023)
Weeks tracked167
Tracking sinceApr 19, 2023

Price History

1W

0.0%

1M

+0.1%

3M

-0.1%

6M

+3.9%

1Y

+3.9%

3Y

+16.1%

5Y

N/A

All

+16.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ZORYVE 0.3% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for ZORYVE 0.3% CREAM, manufactured by Arcutis Biotherapeutics, Inc., is $15.3781 per GM (NDC 80610013060), effective Jun 24, 2026.

How has the price of ZORYVE 0.3% CREAM changed over time?

Over the history we have for it, the NADAC for ZORYVE 0.3% CREAM has risen 16.1%. It has been tracked across 167 weekly CMS publications since Apr 19, 2023.

What are the highest and lowest recorded NADAC prices for ZORYVE 0.3% CREAM?

Since Apr 19, 2023, the NADAC for ZORYVE 0.3% CREAM has ranged from a low of $13.2416 (Apr 19, 2023) to a high of $15.3897 (May 13, 2026), with a median of $14.2745 per GM.

Are there cheaper alternatives to ZORYVE 0.3% CREAM?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as ZORYVE 0.3% CREAM, but none are currently priced below it.

Who manufactures ZORYVE 0.3% CREAM?

ZORYVE 0.3% CREAM (NDC 80610013060) is labeled by Arcutis Biotherapeutics, Inc., and CMS classifies it as a brand product.