Product Information
DIPHENHYDRAMINE 12.5 MG/5 ML is a generic product labeled by Kesin Pharma Corporation, priced at $0.0174 per ML under NDC 81033002916. Its NADAC has been published 49 times since Oct 29, 2025.
Strength
12.5 mg/5mL
Manufacturer
Kesin Pharma CorporationNDC
81033002916
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DIPHENHYDRAMINE HCLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
3/4/2025
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has been published 49 times since Oct 29, 2025, and over the history we have for it it has risen 41.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0174 per ML |
|---|---|
| All-time high | $0.0178 (Feb 11, 2026) |
| All-time low | $0.0123 (Oct 29, 2025) |
| 52-week high | $0.0178 |
| 52-week low | $0.0123 |
| Median price | $0.0170 |
| Average price | $0.0165 |
| Largest weekly change | +17.4% (Nov 19, 2025) |
| Weeks tracked | 49 |
| Tracking since | Oct 29, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Diphenhydramine HCl Oral Solution market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Kesin Pharma Corporation manufacturer profile
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Drug market
Diphenhydramine HCl Oral Solution market comparison
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Therapeutic class
Histamine-1 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 12.5 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 12.5 MG/5 ML, manufactured by Kesin Pharma Corporation, is $0.0174 per ML (NDC 81033002916), effective Sep 30, 2026.
How has the price of DIPHENHYDRAMINE 12.5 MG/5 ML changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has risen 41.4%. It has been tracked across 49 weekly CMS publications since Oct 29, 2025.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 12.5 MG/5 ML?
Since Oct 29, 2025, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has ranged from a low of $0.0123 (Oct 29, 2025) to a high of $0.0178 (Feb 11, 2026), with a median of $0.0170 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 12.5 MG/5 ML?
No other NADAC-published product currently shares the active ingredient and strength of DIPHENHYDRAMINE 12.5 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures DIPHENHYDRAMINE 12.5 MG/5 ML?
DIPHENHYDRAMINE 12.5 MG/5 ML (NDC 81033002916) is labeled by Kesin Pharma Corporation, and CMS classifies it as a generic product.