Product Information
ISONIAZID 300 MG TABLET is a generic product labeled by Omnivium Pharmaceuticals LLC, priced at $3.4020 per EA under NDC 81665010810. Its NADAC has been published 72 times since May 21, 2025.
FDA first approved this application on Jun 26, 1997. Its Orange Book therapeutic-equivalence code is AA.
Strength
300 mg/1
Manufacturer
Omnivium Pharmaceuticals LLCNDC
81665010810
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ISONIAZIDApproval Type
Generic (ANDA)
FDA Application
ANDA040090FDA Approved
6/26/1997
TE Code
AA
On Market Since
10/15/2024
Pharmacological Classes
Price Statistics
The NADAC for ISONIAZID 300 MG TABLET has been published 72 times since May 21, 2025, and over the history we have for it it has risen 8.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.4020 per EA |
|---|---|
| All-time high | $3.5124 (Aug 12, 2026) |
| All-time low | $2.6149 (Nov 19, 2025) |
| 52-week high | $3.5124 |
| 52-week low | $2.6149 |
| Median price | $3.2294 |
| Average price | $3.1616 |
| Largest weekly change | +18.7% (Dec 31, 2025) |
| Weeks tracked | 72 |
| Tracking since | May 21, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Omnivium Pharmaceuticals LLC manufacturer profile
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Drug market
isoniazid market comparison
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Therapeutic class
Antimycobacterial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ISONIAZID 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ISONIAZID 300 MG TABLET, manufactured by Omnivium Pharmaceuticals LLC, is $3.4020 per EA (NDC 81665010810), effective Sep 30, 2026.
How has the price of ISONIAZID 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for ISONIAZID 300 MG TABLET has risen 8.8%. It has been tracked across 72 weekly CMS publications since May 21, 2025.
What are the highest and lowest recorded NADAC prices for ISONIAZID 300 MG TABLET?
Since May 21, 2025, the NADAC for ISONIAZID 300 MG TABLET has ranged from a low of $2.6149 (Nov 19, 2025) to a high of $3.5124 (Aug 12, 2026), with a median of $3.2294 per EA.
Are there cheaper alternatives to ISONIAZID 300 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISONIAZID 300 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ISONIAZID 300 MG TABLET?
ISONIAZID 300 MG TABLET (NDC 81665010810) is labeled by Omnivium Pharmaceuticals LLC, and CMS classifies it as a generic product.