Product Information

ISONIAZID 300 MG TABLET is a generic product labeled by Omnivium Pharmaceuticals LLC, priced at $3.4917 per EA under NDC 81665010830. Its NADAC has been published 66 times since May 21, 2025.

FDA first approved this application on Jun 26, 1997. Its Orange Book therapeutic-equivalence code is AA.

ISONIAZID 300 MG TABLET

isoniazid
$3.4917per EA

Strength

300 mg/1

NDC

81665010830

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ISONIAZID

Approval Type

Generic (ANDA)

FDA Application

ANDA040090

FDA Approved

6/26/1997

TE Code

AA

On Market Since

10/15/2024

Pharmacological Classes

Price Statistics

The NADAC for ISONIAZID 300 MG TABLET has been published 66 times since May 21, 2025, and over the history we have for it it has risen 11.6%. The table below summarizes its recorded NADAC range and movement.

Current price$3.4917 per EA
All-time high$3.5124 (Aug 12, 2026)
All-time low$2.6149 (Nov 19, 2025)
52-week high$3.5124
52-week low$2.6149
Median price$3.2294
Average price$3.1343
Largest weekly change+18.7% (Dec 31, 2025)
Weeks tracked66
Tracking sinceMay 21, 2025

Price History

1W

-0.6%

1M

-0.6%

3M

+4.0%

6M

+8.1%

1Y

+16.5%

3Y

N/A

5Y

N/A

All

+11.6%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ISONIAZID 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ISONIAZID 300 MG TABLET, manufactured by Omnivium Pharmaceuticals LLC, is $3.4917 per EA (NDC 81665010830), effective Aug 19, 2026.

How has the price of ISONIAZID 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for ISONIAZID 300 MG TABLET has risen 11.6%. It has been tracked across 66 weekly CMS publications since May 21, 2025.

What are the highest and lowest recorded NADAC prices for ISONIAZID 300 MG TABLET?

Since May 21, 2025, the NADAC for ISONIAZID 300 MG TABLET has ranged from a low of $2.6149 (Nov 19, 2025) to a high of $3.5124 (Aug 12, 2026), with a median of $3.2294 per EA.

Are there cheaper alternatives to ISONIAZID 300 MG TABLET?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISONIAZID 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ISONIAZID 300 MG TABLET?

ISONIAZID 300 MG TABLET (NDC 81665010830) is labeled by Omnivium Pharmaceuticals LLC, and CMS classifies it as a generic product.