Product Information
LOTEPREDNOL 0.5% OPHTHALMC GEL is a generic product labeled by Bausch & Lomb Americas Inc., priced at $18.1880 per GM under NDC 82260050801. Its NADAC has been published 73 times since May 14, 2025.
FDA first approved this application on Sep 28, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/g
Manufacturer
Bausch & Lomb Americas Inc.NDC
82260050801
Classification
Generic
Dosage Form
GEL
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA202872FDA Approved
9/28/2012
TE Code
AB
On Market Since
6/30/2023
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL 0.5% OPHTHALMC GEL has been published 73 times since May 14, 2025, and over the history we have for it it has risen 22.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.1880 per GM |
|---|---|
| All-time high | $18.1880 (Sep 30, 2026) |
| All-time low | $14.0549 (Jun 18, 2025) |
| 52-week high | $18.1880 |
| 52-week low | $14.2657 |
| Median price | $14.8251 |
| Average price | $15.0005 |
| Largest weekly change | +13.1% (Sep 23, 2026) |
| Weeks tracked | 73 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Bausch & Lomb Americas Inc. manufacturer profile
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Drug market
loteprednol etabonate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOTEPREDNOL 0.5% OPHTHALMC GEL?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL 0.5% OPHTHALMC GEL, manufactured by Bausch & Lomb Americas Inc., is $18.1880 per GM (NDC 82260050801), effective Sep 30, 2026.
How has the price of LOTEPREDNOL 0.5% OPHTHALMC GEL changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL 0.5% OPHTHALMC GEL has risen 22.8%. It has been tracked across 73 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL 0.5% OPHTHALMC GEL?
Since May 14, 2025, the NADAC for LOTEPREDNOL 0.5% OPHTHALMC GEL has ranged from a low of $14.0549 (Jun 18, 2025) to a high of $18.1880 (Sep 30, 2026), with a median of $14.8251 per GM.
Are there cheaper alternatives to LOTEPREDNOL 0.5% OPHTHALMC GEL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOTEPREDNOL 0.5% OPHTHALMC GEL in a comparable dosage form, but none are currently priced below it.
Who manufactures LOTEPREDNOL 0.5% OPHTHALMC GEL?
LOTEPREDNOL 0.5% OPHTHALMC GEL (NDC 82260050801) is labeled by Bausch & Lomb Americas Inc., and CMS classifies it as a generic product.