Dihydroergotamine Mesylate
7 NDCs across 5 manufacturers|7 Generic,0 Brand
Dihydroergotamine Mesylate is used to treat cluster headache, orthostatic hypotension, migraine disorders, postpartum hemorrhage and xerostomia, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Apr 28, 2003. FDA's Orange Book lists 5 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $29 million on Dihydroergotamine Mesylate across 19,000 claims for 3,974 beneficiaries.
Dihydroergotamine Mesylate is available as 7 NDCs from 5 manufacturers (7 generic, 0 brand), with NADAC prices from $30.15 to $68.01 per ML — the most expensive product costs about 2.3× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
7
7G / 0B
Manufacturers
5
competing in market
Price Spread
$30.15 – $68.01
per ML
7d Activity
avg -4.3% WoW · of 7 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
5 manufacturers producing DIHYDROERGOTAMINE MESYLATE
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
DIHYDROERGOTAMINE 1 MG/ML AMP | $68.0082 per ML | — |
DIHYDROERGOTAMINE 1 MG/ML AMP | $68.0082 per ML | — |
DIHYDROERGOTAMINE 1 MG/ML AMP | $52.6420 per ML | — |
DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY | $32.7695 per ML | — |
DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY | $30.1478 per ML | -4.35% |
DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY | $30.1478 per ML | -4.35% |
DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY | $30.1478 per ML | -4.35% |
Frequently Asked Questions
What is Dihydroergotamine Mesylate used to treat?
Dihydroergotamine Mesylate is used to treat cluster headache, orthostatic hypotension, migraine disorders, postpartum hemorrhage and xerostomia, per the National Library of Medicine's MED-RT classification.
When did Dihydroergotamine Mesylate become available as a generic?
FDA approved the first generic Dihydroergotamine Mesylate (ANDA) on Apr 28, 2003. The Orange Book currently lists 5 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Dihydroergotamine Mesylate?
In 2024, Medicare Part D spent $29 million on Dihydroergotamine Mesylate across 19,000 claims for 3,974 beneficiaries.
How many Dihydroergotamine Mesylate products are on the market?
The Dihydroergotamine Mesylate drug market contains 7 NDCs from 5 manufacturers — 7 generic and 0 brand products.
What is the price range for Dihydroergotamine Mesylate?
NADAC reference prices for Dihydroergotamine Mesylate range from $30.1478 to $68.0082 per ML — the most expensive product costs about 2.3× the cheapest.
Which manufacturers make Dihydroergotamine Mesylate?
5 manufacturers list Dihydroergotamine Mesylate in NADAC. Ranked by number of NDCs, the largest are Hikma Pharmaceuticals USA Inc. (2), Provepharm Inc. (2), Oceanside Pharmaceuticals (1), Trifluent Pharma LLC (1), Advagen Pharma Ltd. (1).
How has the price of Dihydroergotamine Mesylate changed recently?
Over the past 7 days, 0 Dihydroergotamine Mesylate NDCs rose and 3 fell, with a market-wide average change of -4.3%.