Historical record - last NADAC effective date: 8/21/2024
Product Information
DIHYDROERGOTAMINE 1 MG/ML AMP is a generic product labeled by Provepharm Inc., priced at $68.0082 per ML under NDC 81284041110. Its NADAC has been published 57 times since Jul 17, 2024.
FDA first approved this application on Jan 7, 2020. Its Orange Book therapeutic-equivalence code is AP.
Strength
1 mg/mL
Manufacturer
Provepharm Inc.NDC
81284041110
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
8/21/2024
Active Ingredients
DIHYDROERGOTAMINE MESYLATEApproval Type
Generic (ANDA)
FDA Application
ANDA212046FDA Approved
1/7/2020
TE Code
AP
On Market Since
9/30/2021
Pharmacological Classes
Price Statistics
The NADAC for DIHYDROERGOTAMINE 1 MG/ML AMP has been published 57 times since Jul 17, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $68.0082 per ML |
|---|---|
| All-time high | $68.0082 (Aug 13, 2025) |
| All-time low | $68.0082 (Jul 17, 2024) |
| Median price | $68.0082 |
| Average price | $68.0082 |
| Largest weekly change | 0.0% (Jul 24, 2024) |
| Weeks tracked | 57 |
| Tracking since | Jul 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
N/A
All
0.0%
Last surveyed Aug 13, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 23% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIHYDROERGOTAMINE 1 MG/ML AMP?
The current National Average Drug Acquisition Cost (NADAC) for DIHYDROERGOTAMINE 1 MG/ML AMP, manufactured by Provepharm Inc., is $68.0082 per ML (NDC 81284041110), effective Aug 13, 2025.
How has the price of DIHYDROERGOTAMINE 1 MG/ML AMP changed over time?
Over the history we have for it, the NADAC for DIHYDROERGOTAMINE 1 MG/ML AMP has held within roughly two percent of its current level. It has been tracked across 57 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for DIHYDROERGOTAMINE 1 MG/ML AMP?
Since Jul 17, 2024, the NADAC for DIHYDROERGOTAMINE 1 MG/ML AMP has ranged from a low of $68.0082 (Jul 17, 2024) to a high of $68.0082 (Aug 13, 2025), with a median of $68.0082 per ML.
Are there cheaper alternatives to DIHYDROERGOTAMINE 1 MG/ML AMP?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIHYDROERGOTAMINE 1 MG/ML AMP, is $52.6420 per ML — about 23% below DIHYDROERGOTAMINE 1 MG/ML AMP.
Who manufactures DIHYDROERGOTAMINE 1 MG/ML AMP?
DIHYDROERGOTAMINE 1 MG/ML AMP (NDC 81284041110) is labeled by Provepharm Inc., and CMS classifies it as a generic product.