Product Information

DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY is a generic product labeled by Advagen Pharma Ltd., priced at $30.1478 per ML under NDC 72888009619. Its NADAC has been published 142 times since Dec 6, 2023.

FDA first approved this application on Jun 22, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY

Dihydroergotamine mesylate
$30.1478per ML

Strength

4 mg/mL

NDC

72888009619

Classification

Generic

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

DIHYDROERGOTAMINE MESYLATE

Approval Type

Generic (ANDA)

FDA Application

ANDA216881

FDA Approved

6/22/2023

TE Code

AB

On Market Since

6/23/2023

Pharmacological Classes

Price Statistics

The NADAC for DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY has been published 142 times since Dec 6, 2023, and over the history we have for it it has declined 11.9%. The table below summarizes its recorded NADAC range and movement.

Current price$30.1478 per ML
All-time high$70.5602 (May 15, 2024)
All-time low$30.1478 (Aug 19, 2026)
52-week high$35.4287
52-week low$30.1478
Median price$34.2118
Average price$35.7871
Largest weekly change+106.2% (Apr 17, 2024)
Weeks tracked142
Tracking sinceDec 6, 2023

Price History

1W

-4.3%

1M

-4.3%

3M

-14.4%

6M

-10.4%

1Y

-7.6%

3Y

N/A

5Y

N/A

All

-11.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY, manufactured by Advagen Pharma Ltd., is $30.1478 per ML (NDC 72888009619), effective Aug 19, 2026.

How has the price of DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY has declined 11.9%. It has been tracked across 142 weekly CMS publications since Dec 6, 2023.

What are the highest and lowest recorded NADAC prices for DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY?

Since Dec 6, 2023, the NADAC for DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY has ranged from a low of $30.1478 (Aug 19, 2026) to a high of $70.5602 (May 15, 2024), with a median of $34.2118 per ML.

Are there cheaper alternatives to DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY in a comparable dosage form, but none are currently priced below it.

Who manufactures DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY?

DIHYDROERGOTAMINE MESYLATE 4 MG/ML NASAL SPRAY (NDC 72888009619) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.