Estrogens, Conjugated
12 NDCs across 2 manufacturers|4 Generic,8 Brand
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The brand product was first FDA-approved before 1982, and the first generic was approved Oct 15, 2025. FDA's Orange Book lists 10 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $255 million on Estrogens, Conjugated across 611,000 claims for 232,000 beneficiaries.
Estrogens, Conjugated is available as 12 NDCs from 2 manufacturers (4 generic, 8 brand), with NADAC prices from $5.37 to $6.96 per EA — a 29% difference between cheapest and most expensive. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
12
4G / 8B
Manufacturers
2
competing in market
Price Spread
$5.37 – $6.96
per EA
7d Activity
avg -0.5% WoW · of 12 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. manufacturer profile
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Lead class
Estrogen class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
2 manufacturers producing ESTROGENS, CONJUGATED
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
PREMARIN 0.45 MG TABLET | $6.9558 per EA | 0.00% |
PREMARIN 1.25 MG TABLET | $6.9537 per EA | -0.04% |
PREMARIN 1.25 MG TABLET | $6.9537 per EA | -0.04% |
PREMARIN 0.3 MG TABLET | $6.9474 per EA | -0.04% |
PREMARIN 0.3 MG TABLET | $6.9474 per EA | -0.04% |
PREMARIN 0.625 MG TABLET | $6.9429 per EA | 0.00% |
PREMARIN 0.625 MG TABLET | $6.9429 per EA | 0.00% |
PREMARIN 0.9 MG TABLET | $6.9313 per EA | -0.03% |
CONJUGATED ESTROGENS 0.45 MG TB | $5.4808 per EA | -2.89% |
CONJUGATED ESTROGENS 1.25 MG TB | $5.4766 per EA | -2.25% |
CONJUGATED ESTROGEN 0.625 MG TB | $5.4698 per EA | -2.00% |
CONJUGATED ESTROGENS 0.3 MG TB | $5.3728 per EA | +1.12% |
Frequently Asked Questions
When did Estrogens, Conjugated become available as a generic?
FDA approved the first generic Estrogens, Conjugated (ANDA) on Oct 15, 2025. The Orange Book currently lists 10 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Estrogens, Conjugated?
In 2024, Medicare Part D spent $255 million on Estrogens, Conjugated across 611,000 claims for 232,000 beneficiaries.
How many Estrogens, Conjugated products are on the market?
The Estrogens, Conjugated drug market contains 12 NDCs from 2 manufacturers — 4 generic and 8 brand products.
What is the price range for Estrogens, Conjugated?
NADAC reference prices for Estrogens, Conjugated range from $5.3728 to $6.9558 per EA — a 29% difference between cheapest and most expensive.
Is generic Estrogens, Conjugated cheaper than brand?
The average generic NADAC for Estrogens, Conjugated is $5.4500 per EA, versus $6.9469 for brand-labeled products — generic is about 22% cheaper on average.
Which manufacturers make Estrogens, Conjugated?
2 manufacturers list Estrogens, Conjugated in NADAC. Ranked by number of NDCs, the largest are Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. (8), Ingenus Pharmaceuticals LLC (4).
How has the price of Estrogens, Conjugated changed recently?
Over the past 7 days, 1 Estrogens, Conjugated NDC rose and 8 fell, with a market-wide average change of -0.5%.