Product Information
PREMARIN 0.45 MG TABLET is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $6.9653 per EA under NDC 00046110181. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
.45 mg/1
NDC
00046110181
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ESTROGENS, CONJUGATEDApproval Type
New Drug (NDA)
FDA Application
NDA004782On Market Since
1/1/2006
Pharmacological Classes
Price Statistics
The NADAC for PREMARIN 0.45 MG TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 149.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.9653 per EA |
|---|---|
| All-time high | $6.9689 (Jun 10, 2026) |
| All-time low | $2.7943 (Nov 28, 2013) |
| 52-week high | $6.9689 |
| 52-week low | $6.7461 |
| Median price | $5.6541 |
| Average price | $5.3935 |
| Largest weekly change | +9.4% (Jun 11, 2014) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PREMARIN 0.45 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PREMARIN 0.45 MG TABLET, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $6.9653 per EA (NDC 00046110181), effective Jun 24, 2026.
How has the price of PREMARIN 0.45 MG TABLET changed over time?
Over the history we have for it, the NADAC for PREMARIN 0.45 MG TABLET has risen 149.3%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PREMARIN 0.45 MG TABLET?
Since Nov 28, 2013, the NADAC for PREMARIN 0.45 MG TABLET has ranged from a low of $2.7943 (Nov 28, 2013) to a high of $6.9689 (Jun 10, 2026), with a median of $5.6541 per EA.
Are there cheaper alternatives to PREMARIN 0.45 MG TABLET?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, CONJUGATED ESTROGENS 0.45 MG TB, is $5.8476 per EA — about 16% below PREMARIN 0.45 MG TABLET.
Who manufactures PREMARIN 0.45 MG TABLET?
PREMARIN 0.45 MG TABLET (NDC 00046110181) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.
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Same classification