Isosorbide Mononitrate
33 NDCs across 10 manufacturers|33 Generic,0 Brand
Isosorbide Mononitrate is used to treat angina pectoris, coronary disease, cyanosis, diffuse esophageal spasm, gastroesophageal reflux and heart failure, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Dec 30, 1991, and the first generic was approved Sep 22, 1998. FDA's Orange Book lists 27 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $63 million on Isosorbide Mononitrate across 4.9 million claims for 1.2 million beneficiaries.
Isosorbide Mononitrate is available as 33 NDCs from 10 manufacturers (33 generic, 0 brand), with NADAC prices from $0.07 to $2.65 per EA — the most expensive product costs about 39× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
33
33G / 0B
Manufacturers
10
competing in market
Price Spread
$0.07 – $2.65
per EA
7d Activity
avg -2.4% WoW · of 33 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
10 manufacturers producing ISOSORBIDE MONONITRATE(2 pricing outliers)
Frequently Asked Questions
What is Isosorbide Mononitrate used to treat?
Isosorbide Mononitrate is used to treat angina pectoris, coronary disease, cyanosis, diffuse esophageal spasm, gastroesophageal reflux and heart failure, per the National Library of Medicine's MED-RT classification.
When did Isosorbide Mononitrate become available as a generic?
FDA approved the first generic Isosorbide Mononitrate (ANDA) on Sep 22, 1998. The Orange Book currently lists 27 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Isosorbide Mononitrate?
In 2024, Medicare Part D spent $63 million on Isosorbide Mononitrate across 4.9 million claims for 1.2 million beneficiaries.
How many Isosorbide Mononitrate products are on the market?
The Isosorbide Mononitrate drug market contains 33 NDCs from 10 manufacturers — 33 generic and 0 brand products.
What is the price range for Isosorbide Mononitrate?
NADAC reference prices for Isosorbide Mononitrate range from $0.0680 to $2.6478 per EA — the most expensive product costs about 39× the cheapest.
Which manufacturers make Isosorbide Mononitrate?
10 manufacturers list Isosorbide Mononitrate in NADAC. Ranked by number of NDCs, the largest are Torrent Pharmaceuticals Limited (5), Ingenus Pharmaceuticals LLC (5), Edenbridge Pharmaceuticals LLC (5), Aurobindo Pharma Limited (5), Chartwell RX LLC (3).
How has the price of Isosorbide Mononitrate changed recently?
Over the past 7 days, 16 Isosorbide Mononitrate NDCs rose and 15 fell, with a market-wide average change of -2.4%.