Medroxyprogesterone Acetate
40 NDCs across 12 manufacturers|37 Generic,3 Brand
Medroxyprogesterone Acetate is used to treat amenorrhea, breast neoplasms, renal cell carcinoma, endometrial hyperplasia, endometrial neoplasms and hypoventilation, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 14 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $9 million on Medroxyprogesterone Acetate across 397,000 claims for 107,000 beneficiaries.
Medroxyprogesterone Acetate is available as 40 NDCs from 12 manufacturers (37 generic, 3 brand), with NADAC prices from $18.31 to $77.43 per ML — the most expensive product costs about 4.2× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
40
37G / 3B
Manufacturers
12
competing in market
Price Spread
$18.31 – $77.43
per ML, 27 of 40 NDCs
7d Activity
avg +0.3% WoW · of 40 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Amphastar Pharmaceuticals, Inc. manufacturer profile
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Lead class
Progestin class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
12 manufacturers producing MEDROXYPROGESTERONE ACETATE(4 pricing outliers)
Frequently Asked Questions
What is Medroxyprogesterone Acetate used to treat?
Medroxyprogesterone Acetate is used to treat amenorrhea, breast neoplasms, renal cell carcinoma, endometrial hyperplasia, endometrial neoplasms and hypoventilation, per the National Library of Medicine's MED-RT classification.
When did Medroxyprogesterone Acetate become available as a generic?
FDA approved the first generic Medroxyprogesterone Acetate (ANDA) on Jan 1, 1982. The Orange Book currently lists 14 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Medroxyprogesterone Acetate?
In 2024, Medicare Part D spent $9 million on Medroxyprogesterone Acetate across 397,000 claims for 107,000 beneficiaries.
How many Medroxyprogesterone Acetate products are on the market?
The Medroxyprogesterone Acetate drug market contains 40 NDCs from 12 manufacturers — 37 generic and 3 brand products.
What is the price range for Medroxyprogesterone Acetate?
NADAC reference prices for Medroxyprogesterone Acetate range from $18.3134 to $77.4296 per ML — the most expensive product costs about 4.2× the cheapest. 13 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Medroxyprogesterone Acetate cheaper than brand?
The average generic NADAC for Medroxyprogesterone Acetate is $23.9024 per ML, versus $60.2529 for brand-labeled products — brand versions average about 2.5× the generic price.
Which manufacturers make Medroxyprogesterone Acetate?
12 manufacturers list Medroxyprogesterone Acetate in NADAC. Ranked by number of NDCs, the largest are Amphastar Pharmaceuticals, Inc. (6), Mylan Pharmaceuticals Inc. (6), Teva Pharmaceuticals USA Inc. (6), Pharmacia & Upjohn Company LLC (3), Sun Pharmaceutical Industries Inc. (3).
How has the price of Medroxyprogesterone Acetate changed recently?
Over the past 7 days, 13 Medroxyprogesterone Acetate NDCs rose and 12 fell, with a market-wide average change of +0.3%.