Product Information
NICOTINE 21 MG/24HR PATCH is a generic product labeled by Rugby Laboratories, priced at $1.7558 per EA under NDC 00536589653. Its NADAC has been published 477 times since Jul 5, 2017.
FDA first approved this application on Oct 20, 1997.
Strength
21 mg/24h
Manufacturer
Rugby LaboratoriesNDC
00536589653
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
NICOTINEApproval Type
Generic (ANDA)
FDA Application
ANDA074612FDA Approved
10/20/1997
On Market Since
6/25/2024
Pharmacological Classes
Price Statistics
The NADAC for NICOTINE 21 MG/24HR PATCH has been published 477 times since Jul 5, 2017, and over the history we have for it it has risen 3.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7558 per EA |
|---|---|
| All-time high | $1.7987 (Jul 10, 2019) |
| All-time low | $1.2564 (Apr 17, 2024) |
| 52-week high | $1.7719 |
| 52-week low | $1.4808 |
| Median price | $1.6373 |
| Average price | $1.6210 |
| Largest weekly change | -20.6% (Apr 17, 2024) |
| Weeks tracked | 477 |
| Tracking since | Jul 5, 2017 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 11% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NICOTINE 21 MG/24HR PATCH?
The current National Average Drug Acquisition Cost (NADAC) for NICOTINE 21 MG/24HR PATCH, manufactured by Rugby Laboratories, is $1.7558 per EA (NDC 00536589653), effective Aug 19, 2026.
How has the price of NICOTINE 21 MG/24HR PATCH changed over time?
Over the history we have for it, the NADAC for NICOTINE 21 MG/24HR PATCH has risen 3.0%. It has been tracked across 477 weekly CMS publications since Jul 5, 2017.
What are the highest and lowest recorded NADAC prices for NICOTINE 21 MG/24HR PATCH?
Since Jul 5, 2017, the NADAC for NICOTINE 21 MG/24HR PATCH has ranged from a low of $1.2564 (Apr 17, 2024) to a high of $1.7987 (Jul 10, 2019), with a median of $1.6373 per EA.
Are there cheaper alternatives to NICOTINE 21 MG/24HR PATCH?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SM NICOTINE 21 MG/24HR PATCH, is $1.5540 per EA — about 11% below NICOTINE 21 MG/24HR PATCH.
Who manufactures NICOTINE 21 MG/24HR PATCH?
NICOTINE 21 MG/24HR PATCH (NDC 00536589653) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.