Perampanel
32 NDCs across 5 manufacturers|18 Generic,14 Brand
Perampanel is used to treat partial epilepsies, tonic-clonic epilepsy and seizures, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Oct 22, 2012, and the first generic was approved May 23, 2025. FDA's Orange Book lists 27 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $76 million on Perampanel across 60,000 claims for 6,558 beneficiaries.
Perampanel is available as 32 NDCs from 5 manufacturers (18 generic, 14 brand), with NADAC prices from $6.43 to $39.14 per EA — the most expensive product costs about 6.1× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
32
18G / 14B
Manufacturers
5
competing in market
Price Spread
$6.43 – $39.14
per EA, 30 of 32 NDCs
7d Activity
avg -2.0% WoW · of 32 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Catalyst Pharmaceuticals, Inc. manufacturer profile
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Lead class
Noncompetitive AMPA Glutamate Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
5 manufacturers producing PERAMPANEL
Frequently Asked Questions
What is Perampanel used to treat?
Perampanel is used to treat partial epilepsies, tonic-clonic epilepsy and seizures, per the National Library of Medicine's MED-RT classification.
When did Perampanel become available as a generic?
FDA approved the first generic Perampanel (ANDA) on May 23, 2025. The Orange Book currently lists 27 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Perampanel?
In 2024, Medicare Part D spent $76 million on Perampanel across 60,000 claims for 6,558 beneficiaries.
How many Perampanel products are on the market?
The Perampanel drug market contains 32 NDCs from 5 manufacturers — 18 generic and 14 brand products.
What is the price range for Perampanel?
NADAC reference prices for Perampanel range from $6.4317 to $39.1403 per EA — the most expensive product costs about 6.1× the cheapest. 2 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Perampanel cheaper than brand?
The average generic NADAC for Perampanel is $14.5979 per EA, versus $35.8900 for brand-labeled products — brand versions average about 2.5× the generic price.
Which manufacturers make Perampanel?
5 manufacturers list Perampanel in NADAC. Ranked by number of NDCs, the largest are Catalyst Pharmaceuticals, Inc. (7), Eisai Inc. (7), Teva Pharmaceuticals USA Inc. (6), Novadoz Pharmaceuticals LLC (6), Sun Pharmaceutical Industries Inc. (6).
How has the price of Perampanel changed recently?
Over the past 7 days, 13 Perampanel NDCs rose and 18 fell, with a market-wide average change of -2.0%.