Timolol Maleate

52 NDCs across 16 manufacturers|48 Generic,4 Brand

Timolol Maleate is used to treat angina pectoris, open-angle glaucoma, heart failure, hypertension and myocardial infarction, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Apr 11, 1989. FDA's Orange Book lists 15 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $52 million on Timolol Maleate across 3.0 million claims for 837,000 beneficiaries.

Timolol Maleate is available as 52 NDCs from 16 manufacturers (48 generic, 4 brand), with NADAC prices from $0.58 to $80.01 per ML — the most expensive product costs about 137× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

48G / 4B

Manufacturers

competing in market

Price Spread

$0.58 – $80.01

per ML, 45 of 52 NDCs

7d Activity

19↑26↓7 flat

avg -0.2% WoW · of 52 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

16 manufacturers producing TIMOLOL MALEATE(3 pricing outliers)

Bausch & Lomb Americas Inc.

Rising Pharma Holdings Inc.

6 NDCs

$0.7365

avg/unit

Somerset Therapeutics, LLC

6 NDCs

$0.7365

avg/unit

Bausch & Lomb Incorporated

Caplin Steriles Limited

Oceanside Pharmaceuticals

Mylan Pharmaceuticals Inc.

1 NDC

$1.4052

avg/unit

Armas Pharmaceuticals Inc.

Ingenus Pharmaceuticals LLC

Drug Portfolio

52 NDCs total, 52 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
ISTALOL 0.5% EYE DROPS	24208000403	Bausch & Lomb Incorporated	$80.0146 per ML	High Outlier	Brand	—	beta-Adrenergic Blocker
ISTALOL 0.5% EYE DROPS	24208000401	Bausch & Lomb Incorporated	$79.7633 per ML	High Outlier	Brand	—	beta-Adrenergic Blocker
TIMOPTIC-XE 0.5% GEL-SOLUTION	24208081605	Bausch & Lomb Incorporated	$40.0881 per ML	High Outlier	Brand	—	beta-Adrenergic Blocker
TIMOLOL 0.5% EYE DROP	82260004505	Bausch & Lomb Americas Inc.	$23.6549 per ML	High Outlier	Generic	-0.15%	beta-Adrenergic Blocker
TIMOLOL 0.5% EYE DROP	68682004525	Oceanside Pharmaceuticals	$20.9770 per ML	High Outlier	Generic	—	beta-Adrenergic Blocker
TIMOLOL 0.5% EYE DROP	68682004550	Oceanside Pharmaceuticals	$17.7216 per ML	High Outlier	Generic	—	beta-Adrenergic Blocker
TIMOLOL 0.5% EYE DROP	82260004525	Bausch & Lomb Americas Inc.	$16.6750 per ML	High Outlier	Generic	+46.91%	beta-Adrenergic Blocker
TIMOPTIC 0.5% OCUDOSE DROP	24208049968	Bausch & Lomb Incorporated	$10.3155 per EA	High Outlier	Brand	+0.02%	beta-Adrenergic Blocker
TIMOLOL 0.5% GFS GEL-SOLUTION	61314022505	Sandoz Inc.	$10.0659 per ML	—	Generic	-13.99%	beta-Adrenergic Blocker
TIMOLOL 0.5% GEL-SOLUTION	82260081905	Bausch & Lomb Americas Inc.	$10.0659 per ML	High Outlier	Generic	-13.99%	beta-Adrenergic Blocker
TIMOLOL 0.25% GEL-SOLUTION	61314022405	Sandoz Inc.	$6.9868 per ML	—	Generic	-13.19%	beta-Adrenergic Blocker
TIMOLOL 0.25% GEL-SOLUTION	82260081825	Bausch & Lomb Americas Inc.	$6.9868 per ML	High Outlier	Generic	-13.19%	beta-Adrenergic Blocker
TIMOLOL MALEATE 10 MG TABLET	00378022101	Mylan Pharmaceuticals Inc.	$1.4052 per EA	—	Generic	—	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROP	72485060260	Armas Pharmaceuticals Inc.	$1.2411 per EA	—	Generic	—	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROP	42571039871	Micro Labs Limited	$1.1871 per EA	—	Generic	-4.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROP	50742028860	Ingenus Pharmaceuticals LLC	$1.1871 per EA	—	Generic	-4.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROP	82260049605	Bausch & Lomb Americas Inc.	$1.1871 per EA	High Outlier	Generic	-4.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROP	69918060160	Nordic Pharma, Inc.	$1.1871 per EA	—	Generic	-4.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	61314022705	Sandoz Inc.	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	60758080105	Pacific Pharma, Inc.	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	64980051405	Rising Pharma Holdings Inc.	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	65145015201	Caplin Steriles Limited	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	69315032505	Leading Pharma, LLC	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	70069070601	Somerset Therapeutics, LLC	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	70756065615	Lifestar Pharma LLC	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	72603054001	NorthStar Rx LLC	$1.0592 per ML	—	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	82260081305	Bausch & Lomb Americas Inc.	$1.0592 per ML	High Outlier	Generic	+1.79%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	64980051415	Rising Pharma Holdings Inc.	$0.7603 per ML	—	Generic	-2.48%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	70069070801	Somerset Therapeutics, LLC	$0.7603 per ML	—	Generic	-2.48%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	61314022715	Sandoz Inc.	$0.7603 per ML	—	Generic	-2.48%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	65145015401	Caplin Steriles Limited	$0.7603 per ML	—	Generic	-2.48%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	69315032515	Leading Pharma, LLC	$0.7603 per ML	—	Generic	-2.48%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	70069070701	Somerset Therapeutics, LLC	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	69315032510	Leading Pharma, LLC	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	70756065730	Lifestar Pharma LLC	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	64980051401	Rising Pharma Holdings Inc.	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	60758080110	Pacific Pharma, Inc.	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	61314022710	Sandoz Inc.	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.5% EYE DROPS	65145015301	Caplin Steriles Limited	$0.7316 per ML	—	Generic	-0.35%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	70069070101	Somerset Therapeutics, LLC	$0.6610 per ML	—	Generic	-0.46%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	64980051305	Rising Pharma Holdings Inc.	$0.6610 per ML	—	Generic	-0.46%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	70756065415	Lifestar Pharma LLC	$0.6610 per ML	—	Generic	-0.46%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	61314022605	Sandoz Inc.	$0.6610 per ML	—	Generic	-0.46%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	60758080205	Pacific Pharma, Inc.	$0.6610 per ML	—	Generic	-0.46%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	61314022610	Sandoz Inc.	$0.6227 per ML	—	Generic	+1.28%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	70756065530	Lifestar Pharma LLC	$0.6227 per ML	—	Generic	+1.28%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	70069070201	Somerset Therapeutics, LLC	$0.6227 per ML	—	Generic	+1.28%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	64980051301	Rising Pharma Holdings Inc.	$0.6227 per ML	—	Generic	+1.28%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	60758080210	Pacific Pharma, Inc.	$0.6227 per ML	—	Generic	+1.28%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	70069070301	Somerset Therapeutics, LLC	$0.5843 per ML	—	Generic	+3.54%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	61314022615	Sandoz Inc.	$0.5843 per ML	—	Generic	+3.54%	beta-Adrenergic Blocker
TIMOLOL MALEATE 0.25% EYE DROP	64980051315	Rising Pharma Holdings Inc.	$0.5843 per ML	—	Generic	+3.54%	beta-Adrenergic Blocker

Frequently Asked Questions

What is Timolol Maleate used to treat?

Timolol Maleate is used to treat angina pectoris, open-angle glaucoma, heart failure, hypertension and myocardial infarction, per the National Library of Medicine's MED-RT classification.

When did Timolol Maleate become available as a generic?

FDA approved the first generic Timolol Maleate (ANDA) on Apr 11, 1989. The Orange Book currently lists 15 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Timolol Maleate?

In 2024, Medicare Part D spent $52 million on Timolol Maleate across 3.0 million claims for 837,000 beneficiaries.

How many Timolol Maleate products are on the market?

The Timolol Maleate drug market contains 52 NDCs from 16 manufacturers — 48 generic and 4 brand products.

What is the price range for Timolol Maleate?

NADAC reference prices for Timolol Maleate range from $0.5843 to $80.0146 per ML — the most expensive product costs about 137× the cheapest. 7 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Timolol Maleate cheaper than brand?

The average generic NADAC for Timolol Maleate is $3.3276 per ML, versus $66.6220 for brand-labeled products — brand versions average about 20× the generic price.

Which manufacturers make Timolol Maleate?

16 manufacturers list Timolol Maleate in NADAC. Ranked by number of NDCs, the largest are Sandoz Inc. (8), Bausch & Lomb Americas Inc. (6), Rising Pharma Holdings Inc. (6), Somerset Therapeutics, LLC (6), Bausch & Lomb Incorporated (4).

How has the price of Timolol Maleate changed recently?

Over the past 7 days, 19 Timolol Maleate NDCs rose and 26 fell, with a market-wide average change of -0.2%.