Product Information
ISTALOL 0.5% EYE DROPS is a brand product labeled by Bausch & Lomb Incorporated, priced at $80.0649 per ML under NDC 24208000403. Its NADAC has been published 506 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the Timolol Maleate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
5 mg/mL
Manufacturer
Bausch & Lomb IncorporatedNDC
24208000403
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
TIMOLOL MALEATEApproval Type
New Drug (NDA)
FDA Application
NDA021516On Market Since
8/2/2004
Pharmacological Classes
Price Statistics
The NADAC for ISTALOL 0.5% EYE DROPS has been published 506 times since Nov 28, 2013, and over the history we have for it it has risen 107.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $80.0649 per ML |
|---|---|
| All-time high | $80.1365 (Aug 13, 2025) |
| All-time low | $38.6690 (Nov 28, 2013) |
| 52-week high | $80.1365 |
| 52-week low | $80.0092 |
| Median price | $62.5090 |
| Average price | $63.5156 |
| Largest weekly change | +10.0% (Jan 14, 2015) |
| Weeks tracked | 506 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ISTALOL 0.5% EYE DROPS?
The current National Average Drug Acquisition Cost (NADAC) for ISTALOL 0.5% EYE DROPS, manufactured by Bausch & Lomb Incorporated, is $80.0649 per ML (NDC 24208000403), effective Jun 24, 2026.
How has the price of ISTALOL 0.5% EYE DROPS changed over time?
Over the history we have for it, the NADAC for ISTALOL 0.5% EYE DROPS has risen 107.1%. It has been tracked across 506 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ISTALOL 0.5% EYE DROPS?
Since Nov 28, 2013, the NADAC for ISTALOL 0.5% EYE DROPS has ranged from a low of $38.6690 (Nov 28, 2013) to a high of $80.1365 (Aug 13, 2025), with a median of $62.5090 per ML.
Are there cheaper alternatives to ISTALOL 0.5% EYE DROPS?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TIMOLOL MALEATE 0.5% EYE DROPS, is $0.7448 per ML — about 99% below ISTALOL 0.5% EYE DROPS.
Who manufactures ISTALOL 0.5% EYE DROPS?
ISTALOL 0.5% EYE DROPS (NDC 24208000403) is labeled by Bausch & Lomb Incorporated, and CMS classifies it as a brand product.
Related Drugs
Same classification