Product Information
JANUMET XR 100-1,000 MG TABLET is a brand product labeled by Merck Sharp & Dohme LLC, priced at $10.5560 per EA under NDC 00006008182. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Feb 2, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1000; 100 mg/1; mg/1
Manufacturer
Merck Sharp & Dohme LLCNDC
00006008182
Classification
Brand
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDE; SITAGLIPTIN PHOSPHATEApproval Type
New Drug (NDA)
FDA Application
NDA202270FDA Approved
2/2/2012
TE Code
AB
On Market Since
2/2/2012
Pharmacological Classes
Price Statistics
The NADAC for JANUMET XR 100-1,000 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 25.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.5560 per EA |
|---|---|
| All-time high | $18.3351 (May 15, 2024) |
| All-time low | $8.4458 (Nov 28, 2013) |
| 52-week high | $10.5590 |
| 52-week low | $10.5550 |
| Median price | $13.7661 |
| Average price | $13.6652 |
| Largest weekly change | -42.4% (Jan 1, 2025) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of JANUMET XR 100-1,000 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for JANUMET XR 100-1,000 MG TABLET, manufactured by Merck Sharp & Dohme LLC, is $10.5560 per EA (NDC 00006008182), effective Aug 19, 2026.
How has the price of JANUMET XR 100-1,000 MG TABLET changed over time?
Over the history we have for it, the NADAC for JANUMET XR 100-1,000 MG TABLET has risen 25.0%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for JANUMET XR 100-1,000 MG TABLET?
Since Nov 28, 2013, the NADAC for JANUMET XR 100-1,000 MG TABLET has ranged from a low of $8.4458 (Nov 28, 2013) to a high of $18.3351 (May 15, 2024), with a median of $13.7661 per EA.
Are there cheaper alternatives to JANUMET XR 100-1,000 MG TABLET?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ZITUVIMET XR 100-1,000 MG TAB, is $10.0694 per EA — about 5% below JANUMET XR 100-1,000 MG TABLET.
Who manufactures JANUMET XR 100-1,000 MG TABLET?
JANUMET XR 100-1,000 MG TABLET (NDC 00006008182) is labeled by Merck Sharp & Dohme LLC, and CMS classifies it as a brand product.