Product Information

BETOPTIC S 0.25% EYE DROP is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $42.8790 per ML under NDC 00078072915. Its NADAC has been published 110 times since Jul 17, 2024.

FDA first approved this application on Dec 29, 1989.

BETOPTIC S 0.25% EYE DROP

betaxolol hydrochloride
$42.8790per ML

Strength

2.8 mg/mL

NDC

00078072915

Classification

Brand

Dosage Form

SUSPENSION/ DROPS

Route

OPHTHALMIC

Effective Date

1/7/2026

Active Ingredients

BETAXOLOL HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA019845

FDA Approved

12/29/1989

On Market Since

1/15/1996

Pharmacological Classes

Adrenergic beta-Antagonists
beta-Adrenergic Blocker

Price Statistics

The NADAC for BETOPTIC S 0.25% EYE DROP has been published 110 times since Jul 17, 2024, and over the history we have for it it has risen 20.9%. The table below summarizes its recorded NADAC range and movement.

Current price$42.8790 per ML
All-time high$42.8790 (Aug 19, 2026)
All-time low$35.4237 (Dec 18, 2024)
52-week high$42.8790
52-week low$38.8501
Median price$38.9306
Average price$39.2258
Largest weekly change+9.9% (Jan 14, 2026)
Weeks tracked110
Tracking sinceJul 17, 2024

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+10.1%

3Y

N/A

5Y

N/A

All

+20.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 1% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 1%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of BETOPTIC S 0.25% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for BETOPTIC S 0.25% EYE DROP, manufactured by Novartis Pharmaceuticals Corporation, is $42.8790 per ML (NDC 00078072915), effective Aug 19, 2026.

How has the price of BETOPTIC S 0.25% EYE DROP changed over time?

Over the history we have for it, the NADAC for BETOPTIC S 0.25% EYE DROP has risen 20.9%. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.

What are the highest and lowest recorded NADAC prices for BETOPTIC S 0.25% EYE DROP?

Since Jul 17, 2024, the NADAC for BETOPTIC S 0.25% EYE DROP has ranged from a low of $35.4237 (Dec 18, 2024) to a high of $42.8790 (Aug 19, 2026), with a median of $38.9306 per ML.

Are there cheaper alternatives to BETOPTIC S 0.25% EYE DROP?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BETOPTIC S 0.25% EYE DROP, is $42.6242 per ML — about 1% below BETOPTIC S 0.25% EYE DROP.

Who manufactures BETOPTIC S 0.25% EYE DROP?

BETOPTIC S 0.25% EYE DROP (NDC 00078072915) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.