Product Information

LACTULOSE 10 GM/15 ML SOLUTION is a generic product labeled by Xttrium Laboratories, Inc., priced at $0.0224 per ML under NDC 00116400516. Its NADAC has been published 154 times since Sep 13, 2023.

FDA first approved this application on Feb 21, 2002. Its Orange Book therapeutic-equivalence code is AA.

LACTULOSE 10 GM/15 ML SOLUTION

Lactulose
$0.0224per ML

Strength

10 g/15mL

NDC

00116400516

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LACTULOSE

Approval Type

Generic (ANDA)

FDA Application

ANDA075911

FDA Approved

2/21/2002

TE Code

AA

On Market Since

7/1/2022

Pharmacological Classes

Acidifying Activity
Osmotic Activity
Osmotic Laxative
Stimulation Large Intestine Fluid/Electrolyte Secretion

Price Statistics

The NADAC for LACTULOSE 10 GM/15 ML SOLUTION has been published 154 times since Sep 13, 2023, and over the history we have for it it has risen 70.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0224 per ML
All-time high$0.0254 (Sep 10, 2025)
All-time low$0.0116 (Apr 17, 2024)
52-week high$0.0254
52-week low$0.0224
Median price$0.0239
Average price$0.0204
Largest weekly change+47.1% (Aug 21, 2024)
Weeks tracked154
Tracking sinceSep 13, 2023

Price History

1W

-1.0%

1M

-1.0%

3M

-5.3%

6M

-7.9%

1Y

-11.8%

3Y

N/A

5Y

N/A

All

+70.2%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 44% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LACTULOSE 10 GM/15 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for LACTULOSE 10 GM/15 ML SOLUTION, manufactured by Xttrium Laboratories, Inc., is $0.0224 per ML (NDC 00116400516), effective Aug 19, 2026.

How has the price of LACTULOSE 10 GM/15 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has risen 70.2%. It has been tracked across 154 weekly CMS publications since Sep 13, 2023.

What are the highest and lowest recorded NADAC prices for LACTULOSE 10 GM/15 ML SOLUTION?

Since Sep 13, 2023, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has ranged from a low of $0.0116 (Apr 17, 2024) to a high of $0.0254 (Sep 10, 2025), with a median of $0.0239 per ML.

Are there cheaper alternatives to LACTULOSE 10 GM/15 ML SOLUTION?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LACTULOSE 10 GM/15 ML SOLUTION, is $0.0126 per ML — about 44% below LACTULOSE 10 GM/15 ML SOLUTION.

Who manufactures LACTULOSE 10 GM/15 ML SOLUTION?

LACTULOSE 10 GM/15 ML SOLUTION (NDC 00116400516) is labeled by Xttrium Laboratories, Inc., and CMS classifies it as a generic product.