Product Information

LACTULOSE 10 GM/15 ML SOLUTION is a generic product labeled by PAI Holdings LLC, priced at $0.0196 per ML under NDC 00121087332. Its NADAC has been published 333 times since Apr 8, 2020.

FDA first approved this application on Jul 30, 1996. Its Orange Book therapeutic-equivalence code is AA.

LACTULOSE 10 GM/15 ML SOLUTION

Lactulose
$0.0196per ML

Strength

10 g/15mL

Manufacturer

PAI Holdings LLC

NDC

00121087332

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LACTULOSE

Approval Type

Generic (ANDA)

FDA Application

ANDA074623

FDA Approved

7/30/1996

TE Code

AA

On Market Since

12/3/2019

Pharmacological Classes

Acidifying Activity
Osmotic Activity
Osmotic Laxative
Stimulation Large Intestine Fluid/Electrolyte Secretion

Price Statistics

The NADAC for LACTULOSE 10 GM/15 ML SOLUTION has been published 333 times since Apr 8, 2020, and over the history we have for it it has risen 36.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0196 per ML
All-time high$0.0199 (Aug 12, 2026)
All-time low$0.0084 (Jul 17, 2024)
52-week high$0.0199
52-week low$0.0168
Median price$0.0142
Average price$0.0145
Largest weekly change+55.5% (Apr 16, 2025)
Weeks tracked333
Tracking sinceApr 8, 2020

Price History

1W

-1.5%

1M

-1.5%

3M

+3.8%

6M

+4.8%

1Y

+8.5%

3Y

+69.8%

5Y

+33.4%

All

+36.6%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 36% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LACTULOSE 10 GM/15 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for LACTULOSE 10 GM/15 ML SOLUTION, manufactured by PAI Holdings LLC, is $0.0196 per ML (NDC 00121087332), effective Aug 19, 2026.

How has the price of LACTULOSE 10 GM/15 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has risen 36.6%. It has been tracked across 333 weekly CMS publications since Apr 8, 2020.

What are the highest and lowest recorded NADAC prices for LACTULOSE 10 GM/15 ML SOLUTION?

Since Apr 8, 2020, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has ranged from a low of $0.0084 (Jul 17, 2024) to a high of $0.0199 (Aug 12, 2026), with a median of $0.0142 per ML.

Are there cheaper alternatives to LACTULOSE 10 GM/15 ML SOLUTION?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LACTULOSE 10 GM/15 ML SOLUTION, is $0.0126 per ML — about 36% below LACTULOSE 10 GM/15 ML SOLUTION.

Who manufactures LACTULOSE 10 GM/15 ML SOLUTION?

LACTULOSE 10 GM/15 ML SOLUTION (NDC 00121087332) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.