Product Information
LIDOCAINE HCL 4% SOLUTION is a generic product labeled by Xttrium Laboratories, Inc., priced at $0.2220 per ML under NDC 00116402550. Its NADAC has been published 33 times since Aug 20, 2025.
FDA first approved this application on Nov 18, 1982. Its Orange Book therapeutic-equivalence code is AT.
Strength
40 mg/mL
Manufacturer
Xttrium Laboratories, Inc.NDC
00116402550
Classification
Generic
Dosage Form
SOLUTION
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
LIDOCAINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087881FDA Approved
11/18/1982
TE Code
AT
On Market Since
11/18/1982
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE HCL 4% SOLUTION has been published 33 times since Aug 20, 2025, and over the history we have for it it has declined 19.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2220 per ML |
|---|---|
| All-time high | $0.3510 (Nov 19, 2025) |
| All-time low | $0.2046 (Jul 22, 2026) |
| 52-week high | $0.3510 |
| 52-week low | $0.2046 |
| Median price | $0.2434 |
| Average price | $0.2512 |
| Largest weekly change | -30.7% (May 27, 2026) |
| Weeks tracked | 33 |
| Tracking since | Aug 20, 2025 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Xttrium Laboratories, Inc. manufacturer profile
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Drug market
Lidocaine Hydrochloride market comparison
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Therapeutic class
Amide Local Anesthetic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LIDOCAINE HCL 4% SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE HCL 4% SOLUTION, manufactured by Xttrium Laboratories, Inc., is $0.2220 per ML (NDC 00116402550), effective Sep 30, 2026.
How has the price of LIDOCAINE HCL 4% SOLUTION changed over time?
Over the history we have for it, the NADAC for LIDOCAINE HCL 4% SOLUTION has declined 19.9%. It has been tracked across 33 weekly CMS publications since Aug 20, 2025.
What are the highest and lowest recorded NADAC prices for LIDOCAINE HCL 4% SOLUTION?
Since Aug 20, 2025, the NADAC for LIDOCAINE HCL 4% SOLUTION has ranged from a low of $0.2046 (Jul 22, 2026) to a high of $0.3510 (Nov 19, 2025), with a median of $0.2434 per ML.
Are there cheaper alternatives to LIDOCAINE HCL 4% SOLUTION?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIDOCAINE HCL 4% SOLUTION in a comparable dosage form, but none are currently priced below it.
Who manufactures LIDOCAINE HCL 4% SOLUTION?
LIDOCAINE HCL 4% SOLUTION (NDC 00116402550) is labeled by Xttrium Laboratories, Inc., and CMS classifies it as a generic product.