Product Information

LIDOCAINE HCL 4% SOLUTION is a generic product labeled by Xttrium Laboratories, Inc., priced at $0.2080 per ML under NDC 00116402550. Its NADAC has been published 27 times since Aug 20, 2025.

FDA first approved this application on Nov 18, 1982. Its Orange Book therapeutic-equivalence code is AT.

LIDOCAINE HCL 4% SOLUTION

Lidocaine Hydrochloride
$0.2080per ML

Strength

40 mg/mL

NDC

00116402550

Classification

Generic

Dosage Form

SOLUTION

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

LIDOCAINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA087881

FDA Approved

11/18/1982

TE Code

AT

On Market Since

11/18/1982

Pharmacological Classes

Price Statistics

The NADAC for LIDOCAINE HCL 4% SOLUTION has been published 27 times since Aug 20, 2025, and over the history we have for it it has declined 25.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2080 per ML
All-time high$0.3510 (Nov 19, 2025)
All-time low$0.2046 (Jul 22, 2026)
52-week high$0.3510
52-week low$0.2046
Median price$0.2767
Average price$0.2597
Largest weekly change-30.7% (May 27, 2026)
Weeks tracked27
Tracking sinceAug 20, 2025

Price History

1W

+1.6%

1M

+1.6%

3M

-40.8%

6M

-40.8%

1Y

-25.0%

3Y

N/A

5Y

N/A

All

-25.0%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LIDOCAINE HCL 4% SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE HCL 4% SOLUTION, manufactured by Xttrium Laboratories, Inc., is $0.2080 per ML (NDC 00116402550), effective Aug 19, 2026.

How has the price of LIDOCAINE HCL 4% SOLUTION changed over time?

Over the history we have for it, the NADAC for LIDOCAINE HCL 4% SOLUTION has declined 25.0%. It has been tracked across 27 weekly CMS publications since Aug 20, 2025.

What are the highest and lowest recorded NADAC prices for LIDOCAINE HCL 4% SOLUTION?

Since Aug 20, 2025, the NADAC for LIDOCAINE HCL 4% SOLUTION has ranged from a low of $0.2046 (Jul 22, 2026) to a high of $0.3510 (Nov 19, 2025), with a median of $0.2767 per ML.

Are there cheaper alternatives to LIDOCAINE HCL 4% SOLUTION?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIDOCAINE HCL 4% SOLUTION in a comparable dosage form, but none are currently priced below it.

Who manufactures LIDOCAINE HCL 4% SOLUTION?

LIDOCAINE HCL 4% SOLUTION (NDC 00116402550) is labeled by Xttrium Laboratories, Inc., and CMS classifies it as a generic product.