Product Information
LACTULOSE 10 GM/15 ML SOLUTION is a generic product labeled by PAI Holdings LLC, priced at $0.0224 per ML under NDC 00121087316. Its NADAC has been published 333 times since Apr 8, 2020.
FDA first approved this application on Jul 30, 1996. Its Orange Book therapeutic-equivalence code is AA.
Strength
10 g/15mL
Manufacturer
PAI Holdings LLCNDC
00121087316
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LACTULOSEApproval Type
Generic (ANDA)
FDA Application
ANDA074623FDA Approved
7/30/1996
TE Code
AA
On Market Since
12/3/2019
Pharmacological Classes
Price Statistics
The NADAC for LACTULOSE 10 GM/15 ML SOLUTION has been published 333 times since Apr 8, 2020, and over the history we have for it it has risen 41.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0224 per ML |
|---|---|
| All-time high | $0.0254 (Sep 10, 2025) |
| All-time low | $0.0116 (Apr 17, 2024) |
| 52-week high | $0.0254 |
| 52-week low | $0.0224 |
| Median price | $0.0151 |
| Average price | $0.0174 |
| Largest weekly change | +47.1% (Aug 21, 2024) |
| Weeks tracked | 333 |
| Tracking since | Apr 8, 2020 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 44% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LACTULOSE 10 GM/15 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for LACTULOSE 10 GM/15 ML SOLUTION, manufactured by PAI Holdings LLC, is $0.0224 per ML (NDC 00121087316), effective Aug 19, 2026.
How has the price of LACTULOSE 10 GM/15 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has risen 41.0%. It has been tracked across 333 weekly CMS publications since Apr 8, 2020.
What are the highest and lowest recorded NADAC prices for LACTULOSE 10 GM/15 ML SOLUTION?
Since Apr 8, 2020, the NADAC for LACTULOSE 10 GM/15 ML SOLUTION has ranged from a low of $0.0116 (Apr 17, 2024) to a high of $0.0254 (Sep 10, 2025), with a median of $0.0151 per ML.
Are there cheaper alternatives to LACTULOSE 10 GM/15 ML SOLUTION?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LACTULOSE 10 GM/15 ML SOLUTION, is $0.0126 per ML — about 44% below LACTULOSE 10 GM/15 ML SOLUTION.
Who manufactures LACTULOSE 10 GM/15 ML SOLUTION?
LACTULOSE 10 GM/15 ML SOLUTION (NDC 00121087316) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.