Product Information

HYDROCORTISONE 2.5% CREAM is a generic product labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., priced at $0.0921 per GM under NDC 00168008031. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 16, 1986. Its Orange Book therapeutic-equivalence code is AT.

HYDROCORTISONE 2.5% CREAM

Hydrocortisone
$0.0921per GM

Strength

25 mg/g

NDC

00168008031

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

HYDROCORTISONE

Approval Type

Generic (ANDA)

FDA Application

ANDA089414

FDA Approved

12/16/1986

TE Code

AT

On Market Since

12/16/1986

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for HYDROCORTISONE 2.5% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 3.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0921 per GM
All-time high$0.2071 (Feb 12, 2014)
All-time low$0.0624 (Nov 20, 2024)
52-week high$0.0930
52-week low$0.0812
Median price$0.0884
Average price$0.0890
Largest weekly change+109.9% (Jan 22, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-1.1%

1M

-1.1%

3M

+0.3%

6M

+6.0%

1Y

+10.0%

3Y

+11.5%

5Y

+0.5%

All

-3.3%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCORTISONE 2.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% CREAM, manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., is $0.0921 per GM (NDC 00168008031), effective Aug 19, 2026.

How has the price of HYDROCORTISONE 2.5% CREAM changed over time?

Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% CREAM has declined 3.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% CREAM?

Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% CREAM has ranged from a low of $0.0624 (Nov 20, 2024) to a high of $0.2071 (Feb 12, 2014), with a median of $0.0884 per GM.

Are there cheaper alternatives to HYDROCORTISONE 2.5% CREAM?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE 2.5% CREAM, is $0.0773 per GM — about 16% below HYDROCORTISONE 2.5% CREAM.

Who manufactures HYDROCORTISONE 2.5% CREAM?

HYDROCORTISONE 2.5% CREAM (NDC 00168008031) is labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., and CMS classifies it as a generic product.