Product Information
HYDROCORTISONE 2.5% CREAM is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $0.2365 per GM under NDC 62559043130. Its NADAC has been published 528 times since Jun 15, 2016.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AT.
Strength
25 mg/g
Manufacturer
ANI Pharmaceuticals, Inc.NDC
62559043130
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
HYDROCORTISONEApproval Type
Generic (ANDA)
FDA Application
ANDA080706FDA Approved
Before 1982
TE Code
AT
On Market Since
4/1/2016
Pharmacological Classes
Price Statistics
The NADAC for HYDROCORTISONE 2.5% CREAM has been published 528 times since Jun 15, 2016, and over the history we have for it it has declined 87.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2365 per GM |
|---|---|
| All-time high | $1.8561 (Jun 15, 2016) |
| All-time low | $0.2040 (Nov 20, 2024) |
| 52-week high | $0.2641 |
| 52-week low | $0.2345 |
| Median price | $0.3621 |
| Average price | $0.5020 |
| Largest weekly change | -23.1% (Nov 20, 2024) |
| Weeks tracked | 528 |
| Tracking since | Jun 15, 2016 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 67% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCORTISONE 2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% CREAM, manufactured by ANI Pharmaceuticals, Inc., is $0.2365 per GM (NDC 62559043130), effective Aug 19, 2026.
How has the price of HYDROCORTISONE 2.5% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% CREAM has declined 87.3%. It has been tracked across 528 weekly CMS publications since Jun 15, 2016.
What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% CREAM?
Since Jun 15, 2016, the NADAC for HYDROCORTISONE 2.5% CREAM has ranged from a low of $0.2040 (Nov 20, 2024) to a high of $1.8561 (Jun 15, 2016), with a median of $0.3621 per GM.
Are there cheaper alternatives to HYDROCORTISONE 2.5% CREAM?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE 2.5% CREAM, is $0.0773 per GM — about 67% below HYDROCORTISONE 2.5% CREAM.
Who manufactures HYDROCORTISONE 2.5% CREAM?
HYDROCORTISONE 2.5% CREAM (NDC 62559043130) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.