Hydrocortisone
86 NDCs across 28 manufacturers|80 Generic,6 Brand
Hydrocortisone is used to treat congenital adrenal hyperplasia, adrenal insufficiency, ulcerative colitis, contact dermatitis, facial dermatoses and foot dermatoses, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 23 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $52 million on Hydrocortisone across 3.0 million claims for 1.6 million beneficiaries.
Hydrocortisone is available as 86 NDCs from 28 manufacturers (80 generic, 6 brand), with NADAC prices from $0.04 to $3.20 per GM — the most expensive product costs about 80× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
86
80G / 6B
Manufacturers
28
competing in market
Price Spread
$0.04 – $3.20
per GM, 50 of 86 NDCs
7d Activity
avg +0.1% WoW · of 86 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Padagis Israel Pharmaceuticals Ltd manufacturer profile
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Lead class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
28 manufacturers producing HYDROCORTISONE(3 pricing outliers)
Frequently Asked Questions
What is Hydrocortisone used to treat?
Hydrocortisone is used to treat congenital adrenal hyperplasia, adrenal insufficiency, ulcerative colitis, contact dermatitis, facial dermatoses and foot dermatoses, per the National Library of Medicine's MED-RT classification.
When did Hydrocortisone become available as a generic?
FDA approved the first generic Hydrocortisone (ANDA) on Jan 1, 1982. The Orange Book currently lists 23 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Hydrocortisone?
In 2024, Medicare Part D spent $52 million on Hydrocortisone across 3.0 million claims for 1.6 million beneficiaries.
How many Hydrocortisone products are on the market?
The Hydrocortisone drug market contains 86 NDCs from 28 manufacturers — 80 generic and 6 brand products.
What is the price range for Hydrocortisone?
NADAC reference prices for Hydrocortisone range from $0.0400 to $3.2043 per GM — the most expensive product costs about 80× the cheapest. 36 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Hydrocortisone cheaper than brand?
The average generic NADAC for Hydrocortisone is $0.1036 per GM, versus $1.3700 for brand-labeled products — brand versions average about 13× the generic price.
Which manufacturers make Hydrocortisone?
28 manufacturers list Hydrocortisone in NADAC. Ranked by number of NDCs, the largest are Padagis Israel Pharmaceuticals Ltd (9), E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. (8), Strategic Sourcing Services LLC (8), Sun Pharmaceutical Industries Inc. (7), ANI Pharmaceuticals, Inc. (6).
How has the price of Hydrocortisone changed recently?
Over the past 7 days, 30 Hydrocortisone NDCs rose and 37 fell, with a market-wide average change of +0.1%.