Product Information

EFUDEX 5% CREAM is a brand product labeled by Bausch Health US LLC, priced at $1.4420 per GM under NDC 00187320447. Its NADAC has been published 276 times since Jan 22, 2014.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AT.

EFUDEX 5% CREAM

Fluorouracil
$1.4420per GM

Strength

2 g/40g

NDC

00187320447

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Effective Date

9/17/2025

Active Ingredients

FLUOROURACIL

Approval Type

New Drug (NDA)

FDA Application

NDA016831

FDA Approved

Before 1982

TE Code

AT

On Market Since

7/29/1970

Pharmacological Classes

Nucleic Acid Synthesis Inhibitors
Nucleoside Metabolic Inhibitor

Price Statistics

The NADAC for EFUDEX 5% CREAM has been published 276 times since Jan 22, 2014, and over the history we have for it it has declined 79.5%. The table below summarizes its recorded NADAC range and movement.

Current price$1.4420 per GM
All-time high$8.0688 (Oct 14, 2015)
All-time low$1.4248 (Mar 18, 2020)
52-week high$1.4420
52-week low$1.4410
Median price$1.4422
Average price$3.4713
Largest weekly change-82.3% (Mar 18, 2020)
Weeks tracked276
Tracking sinceJan 22, 2014

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

+0.1%

3Y

+0.3%

5Y

+1.2%

All

-79.5%

Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 58% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 58%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of EFUDEX 5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for EFUDEX 5% CREAM, manufactured by Bausch Health US LLC, is $1.4420 per GM (NDC 00187320447), effective Oct 1, 2025.

How has the price of EFUDEX 5% CREAM changed over time?

Over the history we have for it, the NADAC for EFUDEX 5% CREAM has declined 79.5%. It has been tracked across 276 weekly CMS publications since Jan 22, 2014.

What are the highest and lowest recorded NADAC prices for EFUDEX 5% CREAM?

Since Jan 22, 2014, the NADAC for EFUDEX 5% CREAM has ranged from a low of $1.4248 (Mar 18, 2020) to a high of $8.0688 (Oct 14, 2015), with a median of $1.4422 per GM.

Are there cheaper alternatives to EFUDEX 5% CREAM?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, FLUOROURACIL 5% CREAM, is $0.6034 per GM — about 58% below EFUDEX 5% CREAM.

Who manufactures EFUDEX 5% CREAM?

EFUDEX 5% CREAM (NDC 00187320447) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.