Product Information
FLUOROURACIL 5% CREAM is a generic product labeled by Encube Ethicals, Inc., priced at $0.5965 per GM under NDC 21922004917. Its NADAC has been published 50 times since Jul 16, 2025.
Strength
2 g/40g
Manufacturer
Encube Ethicals, Inc.NDC
21922004917
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
FLUOROURACILApproval Type
Generic (ANDA)
FDA Application
ANDA216942On Market Since
2/14/2025
Pharmacological Classes
Price Statistics
The NADAC for FLUOROURACIL 5% CREAM has been published 50 times since Jul 16, 2025, and over the history we have for it it has declined 16.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5965 per GM |
|---|---|
| All-time high | $0.7382 (Aug 13, 2025) |
| All-time low | $0.5918 (May 20, 2026) |
| 52-week high | $0.7382 |
| 52-week low | $0.5918 |
| Median price | $0.6172 |
| Average price | $0.6413 |
| Largest weekly change | -7.1% (Sep 17, 2025) |
| Weeks tracked | 50 |
| Tracking since | Jul 16, 2025 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of FLUOROURACIL 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for FLUOROURACIL 5% CREAM, manufactured by Encube Ethicals, Inc., is $0.5965 per GM (NDC 21922004917), effective Jun 24, 2026.
How has the price of FLUOROURACIL 5% CREAM changed over time?
Over the history we have for it, the NADAC for FLUOROURACIL 5% CREAM has declined 16.2%. It has been tracked across 50 weekly CMS publications since Jul 16, 2025.
What are the highest and lowest recorded NADAC prices for FLUOROURACIL 5% CREAM?
Since Jul 16, 2025, the NADAC for FLUOROURACIL 5% CREAM has ranged from a low of $0.5918 (May 20, 2026) to a high of $0.7382 (Aug 13, 2025), with a median of $0.6172 per GM.
Are there cheaper alternatives to FLUOROURACIL 5% CREAM?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as FLUOROURACIL 5% CREAM, but none are currently priced below it.
Who manufactures FLUOROURACIL 5% CREAM?
FLUOROURACIL 5% CREAM (NDC 21922004917) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.
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