Product Information

TORPENZ 5 MG TABLET is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $14.7708 per EA under NDC 00245082330. Its NADAC has been published 101 times since Sep 18, 2024.

FDA first approved this application on Feb 11, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TORPENZ 5 MG TABLET

Everolimus
$14.7708per EA

Strength

5 mg/1

NDC

00245082330

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

4/22/2026

Active Ingredients

EVEROLIMUS

Approval Type

Generic (ANDA)

FDA Application

ANDA214182

FDA Approved

2/11/2021

TE Code

AB

On Market Since

10/1/2021

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A4 Inhibitors
Decreased Immunologic Activity
Kinase Inhibitor
Protein Kinase Inhibitors
mTOR Inhibitor Immunosuppressant
mTOR Inhibitors

Price Statistics

The NADAC for TORPENZ 5 MG TABLET has been published 101 times since Sep 18, 2024, and over the history we have for it it has declined 27.5%. The table below summarizes its recorded NADAC range and movement.

Current price$14.7708 per EA
All-time high$23.3127 (Jan 15, 2025)
All-time low$14.7708 (Dec 17, 2025)
52-week high$17.5117
52-week low$14.7708
Median price$17.5117
Average price$17.5159
Largest weekly change-15.7% (Dec 17, 2025)
Weeks tracked101
Tracking sinceSep 18, 2024

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

-15.7%

3Y

N/A

5Y

N/A

All

-27.5%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TORPENZ 5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TORPENZ 5 MG TABLET, manufactured by Upsher-Smith Laboratories LLC, is $14.7708 per EA (NDC 00245082330), effective Aug 19, 2026.

How has the price of TORPENZ 5 MG TABLET changed over time?

Over the history we have for it, the NADAC for TORPENZ 5 MG TABLET has declined 27.5%. It has been tracked across 101 weekly CMS publications since Sep 18, 2024.

What are the highest and lowest recorded NADAC prices for TORPENZ 5 MG TABLET?

Since Sep 18, 2024, the NADAC for TORPENZ 5 MG TABLET has ranged from a low of $14.7708 (Dec 17, 2025) to a high of $23.3127 (Jan 15, 2025), with a median of $17.5117 per EA.

Are there cheaper alternatives to TORPENZ 5 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TORPENZ 5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures TORPENZ 5 MG TABLET?

TORPENZ 5 MG TABLET (NDC 00245082330) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.