Product Information
SPIRONOLACTONE 50 MG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.0832 per EA under NDC 00378024301. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Aug 20, 2001. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378024301
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
SPIRONOLACTONEApproval Type
Generic (ANDA)
FDA Application
ANDA040424FDA Approved
8/20/2001
TE Code
AB
On Market Since
1/22/2002
Pharmacological Classes
Price Statistics
The NADAC for SPIRONOLACTONE 50 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 63.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0832 per EA |
|---|---|
| All-time high | $0.2347 (Mar 12, 2014) |
| All-time low | $0.0766 (Nov 20, 2024) |
| 52-week high | $0.0972 |
| 52-week low | $0.0832 |
| Median price | $0.1421 |
| Average price | $0.1476 |
| Largest weekly change | +25.8% (Jun 19, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
spironolactone market comparison
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Therapeutic class
Aldosterone Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SPIRONOLACTONE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE 50 MG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $0.0832 per EA (NDC 00378024301), effective Sep 30, 2026.
How has the price of SPIRONOLACTONE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for SPIRONOLACTONE 50 MG TABLET has declined 63.2%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE 50 MG TABLET?
Since Nov 28, 2013, the NADAC for SPIRONOLACTONE 50 MG TABLET has ranged from a low of $0.0766 (Nov 20, 2024) to a high of $0.2347 (Mar 12, 2014), with a median of $0.1421 per EA.
Are there cheaper alternatives to SPIRONOLACTONE 50 MG TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SPIRONOLACTONE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures SPIRONOLACTONE 50 MG TABLET?
SPIRONOLACTONE 50 MG TABLET (NDC 00378024301) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.