Product Information

SPIRONOLACTONE 25 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.0430 per EA under NDC 53746051110. Its NADAC has been published 654 times since Feb 12, 2014.

FDA first approved this application on Jul 2, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

SPIRONOLACTONE 25 MG TABLET

Spironolactone
$0.0430per EA

Strength

25 mg/1

NDC

53746051110

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SPIRONOLACTONE

Approval Type

Generic (ANDA)

FDA Application

ANDA091426

FDA Approved

7/2/2010

TE Code

AB

On Market Since

8/2/2010

Pharmacological Classes

Aldosterone Antagonist
Aldosterone Antagonists

Price Statistics

The NADAC for SPIRONOLACTONE 25 MG TABLET has been published 654 times since Feb 12, 2014, and over the history we have for it it has declined 50.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0430 per EA
All-time high$0.0866 (Feb 12, 2014)
All-time low$0.0410 (Nov 20, 2024)
52-week high$0.0505
52-week low$0.0430
Median price$0.0585
Average price$0.0590
Largest weekly change-20.9% (Nov 20, 2024)
Weeks tracked654
Tracking sinceFeb 12, 2014

Price History

1W

-0.7%

1M

-0.7%

3M

-3.8%

6M

-6.1%

1Y

-14.8%

3Y

-17.8%

5Y

-26.8%

All

-50.3%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SPIRONOLACTONE 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE 25 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.0430 per EA (NDC 53746051110), effective Aug 19, 2026.

How has the price of SPIRONOLACTONE 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for SPIRONOLACTONE 25 MG TABLET has declined 50.3%. It has been tracked across 654 weekly CMS publications since Feb 12, 2014.

What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE 25 MG TABLET?

Since Feb 12, 2014, the NADAC for SPIRONOLACTONE 25 MG TABLET has ranged from a low of $0.0410 (Nov 20, 2024) to a high of $0.0866 (Feb 12, 2014), with a median of $0.0585 per EA.

Are there cheaper alternatives to SPIRONOLACTONE 25 MG TABLET?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as SPIRONOLACTONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures SPIRONOLACTONE 25 MG TABLET?

SPIRONOLACTONE 25 MG TABLET (NDC 53746051110) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.