Product Information
SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.5414 per EA under NDC 00378040305. Its NADAC has been published 473 times since Jun 7, 2017.
Strength
25; 25 mg/1; mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378040305
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; SPIRONOLACTONEApproval Type
Generic (ANDA)
FDA Application
ANDA086513On Market Since
8/3/1979
Pharmacological Classes
Price Statistics
The NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has been published 473 times since Jun 7, 2017, and over the history we have for it it has declined 35.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5414 per EA |
|---|---|
| All-time high | $0.9563 (Sep 13, 2017) |
| All-time low | $0.3906 (Nov 20, 2024) |
| 52-week high | $0.5910 |
| 52-week low | $0.5086 |
| Median price | $0.6824 |
| Average price | $0.6866 |
| Largest weekly change | +37.7% (Aug 21, 2024) |
| Weeks tracked | 473 |
| Tracking since | Jun 7, 2017 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, manufactured by Mylan Pharmaceuticals Inc., is $0.5414 per EA (NDC 00378040305), effective Jun 24, 2026.
How has the price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB changed over time?
Over the history we have for it, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has declined 35.5%. It has been tracked across 473 weekly CMS publications since Jun 7, 2017.
What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
Since Jun 7, 2017, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has ranged from a low of $0.3906 (Nov 20, 2024) to a high of $0.9563 (Sep 13, 2017), with a median of $0.6824 per EA.
Are there cheaper alternatives to SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
3 NADAC-published products share the same active ingredient, strength, and dosage form as SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, but none are currently priced below it.
Who manufactures SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB (NDC 00378040305) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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