Product Information

PENCICLOVIR 1% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $52.2273 per GM under NDC 00378089655. Its NADAC has been published 175 times since Feb 22, 2023.

The High Outlier badge above means this manufacturer's average price in the penciclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

PENCICLOVIR 1% CREAM

penciclovir
$52.2273per GM
High Outlier

Strength

10 mg/g

NDC

00378089655

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

PENCICLOVIR

Approval Type

Authorized Generic (NDA)

FDA Application

NDA020629

On Market Since

11/16/2022

Pharmacological Classes

DNA Polymerase Inhibitors
Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor
Nucleoside Analog

Price Statistics

The NADAC for PENCICLOVIR 1% CREAM has been published 175 times since Feb 22, 2023, and over the history we have for it it has declined 51.4%. The table below summarizes its recorded NADAC range and movement.

Current price$52.2273 per GM
All-time high$108.5362 (Feb 12, 2025)
All-time low$46.3296 (Aug 20, 2025)
52-week high$65.5085
52-week low$46.3296
Median price$91.4302
Average price$85.2065
Largest weekly change-20.8% (Apr 23, 2025)
Weeks tracked175
Tracking sinceFeb 22, 2023

Price History

1W

0.0%

1M

-9.8%

3M

-19.3%

6M

-12.8%

1Y

-6.9%

3Y

-51.4%

5Y

N/A

All

-51.4%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PENCICLOVIR 1% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for PENCICLOVIR 1% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $52.2273 per GM (NDC 00378089655), effective Jun 24, 2026.

How has the price of PENCICLOVIR 1% CREAM changed over time?

Over the history we have for it, the NADAC for PENCICLOVIR 1% CREAM has declined 51.4%. It has been tracked across 175 weekly CMS publications since Feb 22, 2023.

What are the highest and lowest recorded NADAC prices for PENCICLOVIR 1% CREAM?

Since Feb 22, 2023, the NADAC for PENCICLOVIR 1% CREAM has ranged from a low of $46.3296 (Aug 20, 2025) to a high of $108.5362 (Feb 12, 2025), with a median of $91.4302 per GM.

Are there cheaper alternatives to PENCICLOVIR 1% CREAM?

3 NADAC-published products share the same active ingredient, strength, and dosage form as PENCICLOVIR 1% CREAM, but none are currently priced below it.

Who manufactures PENCICLOVIR 1% CREAM?

PENCICLOVIR 1% CREAM (NDC 00378089655) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.