Product Information
DENAVIR 1% CREAM is a brand product labeled by Mylan Pharmaceuticals Inc., priced at $155.0774 per GM under NDC 00378972055. Its NADAC has been published 407 times since Nov 7, 2018.
FDA first approved this application on Sep 24, 1996. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the penciclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
10 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378972055
Classification
Brand
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
PENCICLOVIRApproval Type
New Drug (NDA)
FDA Application
NDA020629FDA Approved
9/24/1996
TE Code
AB
On Market Since
9/24/2018
Pharmacological Classes
Price Statistics
The NADAC for DENAVIR 1% CREAM has been published 407 times since Nov 7, 2018, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $155.0774 per GM |
|---|---|
| All-time high | $156.2449 (Jun 16, 2021) |
| All-time low | $154.4112 (Jun 17, 2026) |
| 52-week high | $155.8578 |
| 52-week low | $154.4112 |
| Median price | $155.7961 |
| Average price | $155.6539 |
| Largest weekly change | +0.6% (Aug 21, 2019) |
| Weeks tracked | 407 |
| Tracking since | Nov 7, 2018 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 68% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DENAVIR 1% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DENAVIR 1% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $155.0774 per GM (NDC 00378972055), effective Aug 19, 2026.
How has the price of DENAVIR 1% CREAM changed over time?
Over the history we have for it, the NADAC for DENAVIR 1% CREAM has held within roughly two percent of its current level. It has been tracked across 407 weekly CMS publications since Nov 7, 2018.
What are the highest and lowest recorded NADAC prices for DENAVIR 1% CREAM?
Since Nov 7, 2018, the NADAC for DENAVIR 1% CREAM has ranged from a low of $154.4112 (Jun 17, 2026) to a high of $156.2449 (Jun 16, 2021), with a median of $155.7961 per GM.
Are there cheaper alternatives to DENAVIR 1% CREAM?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PENCICLOVIR 1% CREAM, is $50.0832 per GM — about 68% below DENAVIR 1% CREAM.
Who manufactures DENAVIR 1% CREAM?
DENAVIR 1% CREAM (NDC 00378972055) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a brand product.