Product Information

METOLAZONE 10 MG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.3802 per EA under NDC 00378617401. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 23, 2003. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METOLAZONE 10 MG TABLET

metolazone
$0.3802per EA

Strength

10 mg/1

NDC

00378617401

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METOLAZONE

Approval Type

Generic (ANDA)

FDA Application

ANDA076698

FDA Approved

12/23/2003

TE Code

AB

On Market Since

10/19/2004

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for METOLAZONE 10 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 45.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3802 per EA
All-time high$2.2491 (Dec 16, 2015)
All-time low$0.3223 (Mar 18, 2026)
52-week high$0.4394
52-week low$0.3223
Median price$1.2826
Average price$1.1524
Largest weekly change+63.7% (May 23, 2018)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+0.2%

1M

+0.2%

3M

+3.5%

6M

+15.9%

1Y

-13.5%

3Y

-37.3%

5Y

-70.0%

All

-45.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the metolazone market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of METOLAZONE 10 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METOLAZONE 10 MG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $0.3802 per EA (NDC 00378617401), effective Aug 19, 2026.

How has the price of METOLAZONE 10 MG TABLET changed over time?

Over the history we have for it, the NADAC for METOLAZONE 10 MG TABLET has declined 45.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for METOLAZONE 10 MG TABLET?

Since Nov 28, 2013, the NADAC for METOLAZONE 10 MG TABLET has ranged from a low of $0.3223 (Mar 18, 2026) to a high of $2.2491 (Dec 16, 2015), with a median of $1.2826 per EA.

Are there cheaper alternatives to METOLAZONE 10 MG TABLET?

No other NADAC-published product currently shares the active ingredient and strength of METOLAZONE 10 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures METOLAZONE 10 MG TABLET?

METOLAZONE 10 MG TABLET (NDC 00378617401) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.