Product Information

DOXEPIN 5% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $6.3191 per GM under NDC 00378811745. Its NADAC has been published 260 times since Mar 13, 2019.

DOXEPIN 5% CREAM

Doxepin Hydrochloride
$6.3191per GM

Strength

50 mg/g

NDC

00378811745

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

DOXEPIN HYDROCHLORIDE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA020126

On Market Since

1/4/2019

Pharmacological Classes

Price Statistics

The NADAC for DOXEPIN 5% CREAM has been published 260 times since Mar 13, 2019, and over the history we have for it it has declined 23.1%. The table below summarizes its recorded NADAC range and movement.

Current price$6.3191 per GM
All-time high$11.7957 (Feb 12, 2020)
All-time low$6.1513 (May 20, 2026)
52-week high$8.3765
52-week low$6.1513
Median price$8.4149
Average price$9.1513
Largest weekly change+34.4% (Oct 23, 2019)
Weeks tracked260
Tracking sinceMar 13, 2019

Price History

1W

0.0%

1M

+2.7%

3M

-5.6%

6M

-22.2%

1Y

-18.2%

3Y

-40.4%

5Y

-40.4%

All

-23.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of DOXEPIN 5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for DOXEPIN 5% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $6.3191 per GM (NDC 00378811745), effective Jun 24, 2026.

How has the price of DOXEPIN 5% CREAM changed over time?

Over the history we have for it, the NADAC for DOXEPIN 5% CREAM has declined 23.1%. It has been tracked across 260 weekly CMS publications since Mar 13, 2019.

What are the highest and lowest recorded NADAC prices for DOXEPIN 5% CREAM?

Since Mar 13, 2019, the NADAC for DOXEPIN 5% CREAM has ranged from a low of $6.1513 (May 20, 2026) to a high of $11.7957 (Feb 12, 2020), with a median of $8.4149 per GM.

Are there cheaper alternatives to DOXEPIN 5% CREAM?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as DOXEPIN 5% CREAM, but none are currently priced below it.

Who manufactures DOXEPIN 5% CREAM?

DOXEPIN 5% CREAM (NDC 00378811745) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.