Product Information
DOXEPIN 5% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $6.5788 per GM under NDC 00378811745. Its NADAC has been published 268 times since Mar 13, 2019.
FDA first approved this application on Apr 1, 1994. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378811745
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DOXEPIN HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020126FDA Approved
4/1/1994
TE Code
AB
On Market Since
1/4/2019
Pharmacological Classes
Price Statistics
The NADAC for DOXEPIN 5% CREAM has been published 268 times since Mar 13, 2019, and over the history we have for it it has declined 19.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.5788 per GM |
|---|---|
| All-time high | $11.7957 (Feb 12, 2020) |
| All-time low | $6.1513 (May 20, 2026) |
| 52-week high | $8.3765 |
| 52-week low | $6.1513 |
| Median price | $8.3765 |
| Average price | $9.0680 |
| Largest weekly change | +34.4% (Oct 23, 2019) |
| Weeks tracked | 268 |
| Tracking since | Mar 13, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DOXEPIN 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DOXEPIN 5% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $6.5788 per GM (NDC 00378811745), effective Aug 19, 2026.
How has the price of DOXEPIN 5% CREAM changed over time?
Over the history we have for it, the NADAC for DOXEPIN 5% CREAM has declined 19.9%. It has been tracked across 268 weekly CMS publications since Mar 13, 2019.
What are the highest and lowest recorded NADAC prices for DOXEPIN 5% CREAM?
Since Mar 13, 2019, the NADAC for DOXEPIN 5% CREAM has ranged from a low of $6.1513 (May 20, 2026) to a high of $11.7957 (Feb 12, 2020), with a median of $8.3765 per GM.
Are there cheaper alternatives to DOXEPIN 5% CREAM?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DOXEPIN 5% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXEPIN 5% CREAM?
DOXEPIN 5% CREAM (NDC 00378811745) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.