Product Information
DOXEPIN 5% CREAM is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $7.1175 per GM under NDC 69238173306. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on Aug 16, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238173306
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
DOXEPIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212357FDA Approved
8/16/2023
TE Code
AB
On Market Since
8/21/2023
Pharmacological Classes
Price Statistics
The NADAC for DOXEPIN 5% CREAM has been published 129 times since Apr 17, 2024, and over the history we have for it it has declined 25.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.1175 per GM |
|---|---|
| All-time high | $9.5612 (May 15, 2024) |
| All-time low | $6.1513 (May 20, 2026) |
| 52-week high | $8.3765 |
| 52-week low | $6.1513 |
| Median price | $7.7135 |
| Average price | $7.6708 |
| Largest weekly change | -12.4% (Jun 19, 2024) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Amneal Pharmaceuticals NY LLC manufacturer profile
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Drug market
Doxepin Hydrochloride market comparison
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Therapeutic class
Tricyclic Antidepressant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DOXEPIN 5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DOXEPIN 5% CREAM, manufactured by Amneal Pharmaceuticals NY LLC, is $7.1175 per GM (NDC 69238173306), effective Sep 30, 2026.
How has the price of DOXEPIN 5% CREAM changed over time?
Over the history we have for it, the NADAC for DOXEPIN 5% CREAM has declined 25.6%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for DOXEPIN 5% CREAM?
Since Apr 17, 2024, the NADAC for DOXEPIN 5% CREAM has ranged from a low of $6.1513 (May 20, 2026) to a high of $9.5612 (May 15, 2024), with a median of $7.7135 per GM.
Are there cheaper alternatives to DOXEPIN 5% CREAM?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as DOXEPIN 5% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures DOXEPIN 5% CREAM?
DOXEPIN 5% CREAM (NDC 69238173306) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.