Product Information
HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1754 per EA under NDC 00406037605. Its NADAC has been published 480 times since Jul 26, 2017.
FDA first approved this application on Mar 31, 2017. Its Orange Book therapeutic-equivalence code is AA.
Strength
300; 5 mg/1; mg/1
Manufacturer
SpecGx LLCNDC
00406037605
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA206718FDA Approved
3/31/2017
TE Code
AA
On Market Since
3/31/2017
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has been published 480 times since Jul 26, 2017, and over the history we have for it it has declined 81.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1754 per EA |
|---|---|
| All-time high | $1.0094 (Mar 14, 2018) |
| All-time low | $0.1228 (Dec 22, 2021) |
| 52-week high | $0.1754 |
| 52-week low | $0.1496 |
| Median price | $0.1946 |
| Average price | $0.3169 |
| Largest weekly change | +77.7% (Sep 23, 2020) |
| Weeks tracked | 480 |
| Tracking since | Jul 26, 2017 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
SpecGx LLC manufacturer profile
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Drug market
Hydrocodone Bitartrate and Acetaminophen market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, manufactured by SpecGx LLC, is $0.1754 per EA (NDC 00406037605), effective Sep 30, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has declined 81.8%. It has been tracked across 480 weekly CMS publications since Jul 26, 2017.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
Since Jul 26, 2017, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has ranged from a low of $0.1228 (Dec 22, 2021) to a high of $1.0094 (Mar 14, 2018), with a median of $0.1946 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, is $0.1496 per EA — about 15% below HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET.
Who manufactures HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET (NDC 00406037605) is labeled by SpecGx LLC, and CMS classifies it as a generic product.