Product Information

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.1496 per EA under NDC 27808011402. Its NADAC has been published 497 times since Aug 17, 2016.

FDA first approved this application on Mar 27, 2013. Its Orange Book therapeutic-equivalence code is AA.

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET

Hydrocodone Bitartrate and Acetaminophen
$0.1496per EA
DEA Schedule CII

Strength

300; 5 mg/1; mg/1

NDC

27808011402

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

2/18/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202214

FDA Approved

3/27/2013

TE Code

AA

On Market Since

4/7/2016

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has been published 497 times since Aug 17, 2016, and over the history we have for it it has declined 86.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1496 per EA
All-time high$1.1464 (Oct 12, 2016)
All-time low$0.1228 (Dec 22, 2021)
52-week high$0.1756
52-week low$0.1496
Median price$0.2340
Average price$0.3998
Largest weekly change+77.7% (Sep 23, 2020)
Weeks tracked497
Tracking sinceAug 17, 2016

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-14.8%

3Y

-11.0%

5Y

-53.1%

All

-86.8%

Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, manufactured by Cranbury Pharmaceuticals, LLC, is $0.1496 per EA (NDC 27808011402), effective Feb 18, 2026.

How has the price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has declined 86.8%. It has been tracked across 497 weekly CMS publications since Aug 17, 2016.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

Since Aug 17, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has ranged from a low of $0.1228 (Dec 22, 2021) to a high of $1.1464 (Oct 12, 2016), with a median of $0.2340 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET (NDC 27808011402) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.