Product Information
METHADONE HCL 10 MG TABLET is a generic product labeled by SpecGx LLC, priced at $0.1752 per EA under NDC 00406577123. Its NADAC has been published 549 times since Feb 17, 2016.
FDA first approved this application on Apr 27, 2004. Its Orange Book therapeutic-equivalence code is AA.
Strength
10 mg/1
Manufacturer
SpecGx LLCNDC
00406577123
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040517FDA Approved
4/27/2004
TE Code
AA
On Market Since
4/27/2004
Pharmacological Classes
Price Statistics
The NADAC for METHADONE HCL 10 MG TABLET has been published 549 times since Feb 17, 2016, and over the history we have for it it has risen 8.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1752 per EA |
|---|---|
| All-time high | $0.2035 (Jul 16, 2025) |
| All-time low | $0.0786 (Dec 22, 2021) |
| 52-week high | $0.1954 |
| 52-week low | $0.1746 |
| Median price | $0.1081 |
| Average price | $0.1245 |
| Largest weekly change | +19.2% (Jun 21, 2023) |
| Weeks tracked | 549 |
| Tracking since | Feb 17, 2016 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHADONE HCL 10 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE HCL 10 MG TABLET, manufactured by SpecGx LLC, is $0.1752 per EA (NDC 00406577123), effective Aug 19, 2026.
How has the price of METHADONE HCL 10 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHADONE HCL 10 MG TABLET has risen 8.5%. It has been tracked across 549 weekly CMS publications since Feb 17, 2016.
What are the highest and lowest recorded NADAC prices for METHADONE HCL 10 MG TABLET?
Since Feb 17, 2016, the NADAC for METHADONE HCL 10 MG TABLET has ranged from a low of $0.0786 (Dec 22, 2021) to a high of $0.2035 (Jul 16, 2025), with a median of $0.1081 per EA.
Are there cheaper alternatives to METHADONE HCL 10 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHADONE HCL 10 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHADONE HCL 10 MG TABLET?
METHADONE HCL 10 MG TABLET (NDC 00406577123) is labeled by SpecGx LLC, and CMS classifies it as a generic product.