Product Information
METHADONE HCL 10 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1752 per EA under NDC 00904741761. Its NADAC has been published 109 times since Jul 24, 2024.
FDA first approved this application on Mar 8, 1983. Its Orange Book therapeutic-equivalence code is AA.
Strength
10 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904741761
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA088109FDA Approved
3/8/1983
TE Code
AA
On Market Since
1/3/2024
Pharmacological Classes
Price Statistics
The NADAC for METHADONE HCL 10 MG TABLET has been published 109 times since Jul 24, 2024, and over the history we have for it it has risen 18.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1752 per EA |
|---|---|
| All-time high | $0.2035 (Jul 16, 2025) |
| All-time low | $0.1473 (Jul 24, 2024) |
| 52-week high | $0.1954 |
| 52-week low | $0.1746 |
| Median price | $0.1835 |
| Average price | $0.1848 |
| Largest weekly change | +17.5% (Aug 21, 2024) |
| Weeks tracked | 109 |
| Tracking since | Jul 24, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHADONE HCL 10 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE HCL 10 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1752 per EA (NDC 00904741761), effective Aug 19, 2026.
How has the price of METHADONE HCL 10 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHADONE HCL 10 MG TABLET has risen 18.9%. It has been tracked across 109 weekly CMS publications since Jul 24, 2024.
What are the highest and lowest recorded NADAC prices for METHADONE HCL 10 MG TABLET?
Since Jul 24, 2024, the NADAC for METHADONE HCL 10 MG TABLET has ranged from a low of $0.1473 (Jul 24, 2024) to a high of $0.2035 (Jul 16, 2025), with a median of $0.1835 per EA.
Are there cheaper alternatives to METHADONE HCL 10 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHADONE HCL 10 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHADONE HCL 10 MG TABLET?
METHADONE HCL 10 MG TABLET (NDC 00904741761) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.